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• W2043283536 abstract "You have accessJournal of UrologyKidney Cancer: Evaluation and Staging1 Apr 2011704 PERCUTANEOUS RENAL MASS BIOPSY: IF THEY'RE POSITIVE, THEY'RE POSITIVE, BUT IF THEY'RE NEGATIVE, BE CAREFUL! A CORRELATION BETWEEN RENAL BIOPSY AND SURGICAL PATHOLOGY Sameer M. Deshmukh, Luiz Sequeira, Francis McGovern, Douglas Dahl, Aria Olumi, Brian Eisner, W. Scott McDougal, Peter Mueller, Anthony Samir, and Adam S Feldman Sameer M. DeshmukhSameer M. Deshmukh Boston, MA More articles by this author , Luiz SequeiraLuiz Sequeira Boston, MA More articles by this author , Francis McGovernFrancis McGovern Boston, MA More articles by this author , Douglas DahlDouglas Dahl Boston, MA More articles by this author , Aria OlumiAria Olumi Boston, MA More articles by this author , Brian EisnerBrian Eisner Boston, MA More articles by this author , W. Scott McDougalW. Scott McDougal Boston, MA More articles by this author , Peter MuellerPeter Mueller Boston, MA More articles by this author , Anthony SamirAnthony Samir Boston, MA More articles by this author , and Adam S FeldmanAdam S Feldman Boston, MA More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.02.1671AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Percutaneous biopsy is an emerging modality in the study of small renal masses. We correlated biopsy pathology results with surgical pathology specimens to investigate the concordance of the pathologic diagnoses. METHODS Under IRB approval, we performed a retrospective review of a database containing 899 patients who had undergone percutaneous biopsy of renal masses at our institution from 1997-2010. Core biopsies were performed using 15–18 gauge cutting needles and fine needle aspirations (FNAs) were performed with 20–23 gauge Chiba needles. 247/899 (27%) patients underwent surgical extirpation of their renal masses. Biopsy and surgical pathologic data were compared. RESULTS 161/247 (65%) patients underwent radical nephrectomy and 86/247 (35%) underwent partial nephrectomy. Mean tumor size was 3.6cm (± 2.3). Median age was 59 years (range 26–88). There were 217 (88%) solid lesions and 30 (12%) cystic lesions. Median time to surgical intervention was 1.68 months (range 0.03–58.7 months). Of 203 percutaneous biopsies demonstrating renal cell carcinoma (RCC), 196 (97%) were RCC on final pathology. Histologic subtype was assessed in 159 biopsy specimens and was correct in 145/159 (91%). Subtype was not specified in 44/203 (22%). 34 lesions identified on biopsy as “benign” or “non-diagnostic” went to surgery because of imaging suspicion or size change; of these, 20 proved to be RCC. Although there is inherent selection bias in this surgical cohort, the sensitivity of renal biopsy for malignancy was 0.89 and the specificity was 0.69. The positive predictive value of biopsy was 0.98 while the negative predictive value was 0.31. Fuhrman grading was reported in 60 percutaneous biopsies. Grade was concordant in 47/60 (78%). CONCLUSIONS Percutaneous renal mass biopsy can accurately determine pathology in suspicious renal masses. However, the low NPV highlights the need for strict follow-up in patients with a non-malignant biopsy result. © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 185Issue 4SApril 2011Page: e283 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.MetricsAuthor Information Sameer M. Deshmukh Boston, MA More articles by this author Luiz Sequeira Boston, MA More articles by this author Francis McGovern Boston, MA More articles by this author Douglas Dahl Boston, MA More articles by this author Aria Olumi Boston, MA More articles by this author Brian Eisner Boston, MA More articles by this author W. Scott McDougal Boston, MA More articles by this author Peter Mueller Boston, MA More articles by this author Anthony Samir Boston, MA More articles by this author Adam S Feldman Boston, MA More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
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• W2043283536 title "704 PERCUTANEOUS RENAL MASS BIOPSY: IF THEY'RE POSITIVE, THEY'RE POSITIVE, BUT IF THEY'RE NEGATIVE, BE CAREFUL! A CORRELATION BETWEEN RENAL BIOPSY AND SURGICAL PATHOLOGY" @default.
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