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• W2043284280 abstract "The increased activity of glutathione peroxidase (GSHPx) in rat lungs is associated with the development of tolerance of the animals to hyperoxia. To understand further the regulation of expression of this enzyme, the molecular structure of the corresponding rat gene was characterized. The rat GSHPx gene consists of two exons interrupted by a single intron of 217 base pairs. The same initiation sites for transcription were found to be utilized in both lung and liver. The promoter of the GSHPx gene contains neither a ‘TATA’ box nor a ‘CAAT’ box. Instead, it comprises two copies of Sp1 binding motif and one copy of AP‐2 binding motif. These features of the promoter may offer a clue to the mechanisms by which the expression of this gene is controlled." @default.
• W2043284280 created "2016-06-24" @default.
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• W2043284280 date "1992-04-13" @default.
• W2043284280 modified "2023-09-25" @default.
• W2043284280 title "Cloning and characterization of the rat glutathione peroxidase gene" @default.
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• W2043284280 doi "https://doi.org/10.1016/0014-5793(92)80198-p" @default.
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