Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043287793> ?p ?o ?g. }
- W2043287793 endingPage "931" @default.
- W2043287793 startingPage "923" @default.
- W2043287793 abstract "Multiply protonated human hemoglobin α-chain species, ranging from [M+4H]4+ to [M + 20H]20+, have been subjected to ion trap collisional activation. Cleavages at 88 of the 140 peptide bonds were indicated, summed over all charge states, although most product ion signals were concentrated in a significantly smaller number of channels. Consistent with previous whole protein ion dissociation studies conducted under similar conditions, the structural information inherent to a given precursor ion was highly sensitive to charge state. A strongly dominant cleavage at D75/M76, also noted previously in beam-type collisional activation studies, was observed for the [M+8H]8+ to [M+11H]11+ precursor ions. At lower charge states, C-terminal aspartic acid cleavages were also prominent but the most abundant products did not arise from the D75/M76 channel. The [M+12H]12+–[M+16H]16+ precursor ions generally yielded the greatest variety of amide bond cleavages. With the exception of the [M+4H]4+ ion, all charge states showed cleavage at the L113/P114 bond. This cleavage proved to be the most prominent dissociation for charge states [M+14H]14+ and higher. The diversity of dissociation channels observed within the charge state range studied potentially provides the opportunity to localize residues associated with variants via a top-down tandem mass spectrometry approach." @default.
- W2043287793 created "2016-06-24" @default.
- W2043287793 creator A5034668945 @default.
- W2043287793 creator A5050822872 @default.
- W2043287793 creator A5052696858 @default.
- W2043287793 date "2006-07-01" @default.
- W2043287793 modified "2023-09-23" @default.
- W2043287793 title "Ion Trap Collision-Induced Dissociation of Human Hemoglobin α-Chain Cations" @default.
- W2043287793 cites W1495926848 @default.
- W2043287793 cites W1963479634 @default.
- W2043287793 cites W1966304675 @default.
- W2043287793 cites W1976645829 @default.
- W2043287793 cites W1979715681 @default.
- W2043287793 cites W1983407717 @default.
- W2043287793 cites W1985426698 @default.
- W2043287793 cites W1991744612 @default.
- W2043287793 cites W1991981952 @default.
- W2043287793 cites W1993428041 @default.
- W2043287793 cites W1995517091 @default.
- W2043287793 cites W1998785079 @default.
- W2043287793 cites W1999848785 @default.
- W2043287793 cites W2000430156 @default.
- W2043287793 cites W2000798961 @default.
- W2043287793 cites W2003510566 @default.
- W2043287793 cites W2003695026 @default.
- W2043287793 cites W2006015763 @default.
- W2043287793 cites W2006468330 @default.
- W2043287793 cites W2008584358 @default.
- W2043287793 cites W2011137687 @default.
- W2043287793 cites W2011677923 @default.
- W2043287793 cites W2014405882 @default.
- W2043287793 cites W2016735256 @default.
- W2043287793 cites W2016766664 @default.
- W2043287793 cites W2018222141 @default.
- W2043287793 cites W2022541411 @default.
- W2043287793 cites W2024606588 @default.
- W2043287793 cites W2028931227 @default.
- W2043287793 cites W2028986128 @default.
- W2043287793 cites W2029881157 @default.
- W2043287793 cites W2036849617 @default.
- W2043287793 cites W2038367741 @default.
- W2043287793 cites W2044803329 @default.
- W2043287793 cites W2045297004 @default.
- W2043287793 cites W2046931015 @default.
- W2043287793 cites W2055385191 @default.
- W2043287793 cites W2055934103 @default.
- W2043287793 cites W2057365035 @default.
- W2043287793 cites W2060119007 @default.
- W2043287793 cites W2062684348 @default.
- W2043287793 cites W2068437485 @default.
- W2043287793 cites W2073389004 @default.
- W2043287793 cites W2073401456 @default.
- W2043287793 cites W2073932244 @default.
- W2043287793 cites W2103558214 @default.
- W2043287793 cites W2119194139 @default.
- W2043287793 cites W2123167404 @default.
- W2043287793 cites W2139904048 @default.
- W2043287793 cites W2145183058 @default.
- W2043287793 cites W2148991677 @default.
- W2043287793 cites W2150093220 @default.
- W2043287793 cites W2153180430 @default.
- W2043287793 cites W2153463169 @default.
- W2043287793 cites W2168090563 @default.
- W2043287793 cites W2335117233 @default.
- W2043287793 cites W2410092882 @default.
- W2043287793 cites W2419502999 @default.
- W2043287793 doi "https://doi.org/10.1016/j.jasms.2006.01.004" @default.
- W2043287793 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16698278" @default.
- W2043287793 hasPublicationYear "2006" @default.
- W2043287793 type Work @default.
- W2043287793 sameAs 2043287793 @default.
- W2043287793 citedByCount "22" @default.
- W2043287793 countsByYear W20432877932014 @default.
- W2043287793 countsByYear W20432877932018 @default.
- W2043287793 countsByYear W20432877932019 @default.
- W2043287793 countsByYear W20432877932020 @default.
- W2043287793 countsByYear W20432877932022 @default.
- W2043287793 crossrefType "journal-article" @default.
- W2043287793 hasAuthorship W2043287793A5034668945 @default.
- W2043287793 hasAuthorship W2043287793A5050822872 @default.
- W2043287793 hasAuthorship W2043287793A5052696858 @default.
- W2043287793 hasBestOaLocation W20432877931 @default.
- W2043287793 hasConcept C102931765 @default.
- W2043287793 hasConcept C106289968 @default.
- W2043287793 hasConcept C113196181 @default.
- W2043287793 hasConcept C145148216 @default.
- W2043287793 hasConcept C147789679 @default.
- W2043287793 hasConcept C162356407 @default.
- W2043287793 hasConcept C176107965 @default.
- W2043287793 hasConcept C178790620 @default.
- W2043287793 hasConcept C185592680 @default.
- W2043287793 hasConcept C2777109674 @default.
- W2043287793 hasConcept C27826464 @default.
- W2043287793 hasConcept C30095370 @default.
- W2043287793 hasConcept C31827203 @default.
- W2043287793 hasConcept C43617362 @default.
- W2043287793 hasConcept C66594872 @default.
- W2043287793 hasConcept C8010536 @default.