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• W2043288535 endingPage "9511" @default.
• W2043288535 startingPage "9497" @default.
• W2043288535 abstract "Noncoding regions within the cluster of immunoglobulin heavy chain constant genes in the human genome contained a number of repeats. In the mu-delta intron, two repeating units were contained. One 442-base-long fragment located JH-mu intron (defined as sigma mu(sigma mu)) occupied the position in the mu-delta intron. The other 1166-base-long fragment located somewhere in front of S (class switch) region of C gamma gene was also found in the mu-delta intron. We defined the repeats in the mu-delta intron as SIGMA (sigma). The polarities of the longer repeats in the genome were opposite between the mu-delta intron and the upstreams of C gamma genes. These inverted copies (defined as sigma gamma 3 and sigma gamma 4), located 6 kb upstream of their respective C gamma's, were apparently transcribed in vitro, via RNA polymerase III and transcripts should have contained tRNA-like structures. Small DNA fragments capable of encoding tRNA-like structures were also found in corresponding regions of mouse Ig C gamma cluster." @default.
• W2043288535 created "2016-06-24" @default.
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• W2043288535 date "1988-01-01" @default.
• W2043288535 modified "2023-10-15" @default.
• W2043288535 title "Sigma region located between C, and C, genes of human immunoglobulin heavy chain: possible involvement of tRNA-like structure in RNA splicing" @default.
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• W2043288535 doi "https://doi.org/10.1093/nar/16.20.9497" @default.
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