Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043304400> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2043304400 endingPage "195" @default.
- W2043304400 startingPage "193" @default.
- W2043304400 abstract "Neuropeptides are heterogeneously distributed throughout the digestive, circulatory, and nervous systems and serve as neurotransmitters, neuromodulators, and hormones. The chapter discusses that neuropeptides are phylogenetically conserved and have been demonstrated to regulate numerous behaviors. They have been hypothesized to be pathologically involved in several psychiatric disorders, including schizophrenia. On the basis of preclinical data, numerous studies have sought to examine the role of neuropeptide systems in schizophrenia. This chapter reviews the clinical data, linking alterations in neuropeptide systems to the etiology, pathophysiology, and treatment of schizophrenia. It describes the clinical trials of data from cerebrospinal fluid (CSF), postmortem and genetic studies. Despite the inherent difficulties associated with human studies, several findings are noteworthy. Postmortem studies support disease-related alterations in several neuropeptide systems in the frontal and temporal cortices. Finally, the only compounds that act directly on neuropeptide systems that have demonstrated therapeutic efficacy in schizophrenia are neurokinin receptor antagonists." @default.
- W2043304400 created "2016-06-24" @default.
- W2043304400 creator A5002961356 @default.
- W2043304400 creator A5005520908 @default.
- W2043304400 creator A5031602380 @default.
- W2043304400 creator A5034415105 @default.
- W2043304400 creator A5039800222 @default.
- W2043304400 creator A5064654923 @default.
- W2043304400 creator A5072303446 @default.
- W2043304400 creator A5091557144 @default.
- W2043304400 date "2004-02-01" @default.
- W2043304400 modified "2023-09-23" @default.
- W2043304400 title "An association study of the neurotensin receptor gene with schizophrenia and clozapine response" @default.
- W2043304400 cites W1968271989 @default.
- W2043304400 cites W1989631259 @default.
- W2043304400 cites W2008356309 @default.
- W2043304400 cites W2011685215 @default.
- W2043304400 cites W2031955038 @default.
- W2043304400 cites W2042936736 @default.
- W2043304400 cites W2085590533 @default.
- W2043304400 cites W2097504226 @default.
- W2043304400 cites W2119226169 @default.
- W2043304400 cites W2143113993 @default.
- W2043304400 cites W267021110 @default.
- W2043304400 doi "https://doi.org/10.1016/s0920-9964(03)00128-2" @default.
- W2043304400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15061255" @default.
- W2043304400 hasPublicationYear "2004" @default.
- W2043304400 type Work @default.
- W2043304400 sameAs 2043304400 @default.
- W2043304400 citedByCount "13" @default.
- W2043304400 countsByYear W20433044002013 @default.
- W2043304400 countsByYear W20433044002018 @default.
- W2043304400 crossrefType "journal-article" @default.
- W2043304400 hasAuthorship W2043304400A5002961356 @default.
- W2043304400 hasAuthorship W2043304400A5005520908 @default.
- W2043304400 hasAuthorship W2043304400A5031602380 @default.
- W2043304400 hasAuthorship W2043304400A5034415105 @default.
- W2043304400 hasAuthorship W2043304400A5039800222 @default.
- W2043304400 hasAuthorship W2043304400A5064654923 @default.
- W2043304400 hasAuthorship W2043304400A5072303446 @default.
- W2043304400 hasAuthorship W2043304400A5091557144 @default.
- W2043304400 hasConcept C118303440 @default.
- W2043304400 hasConcept C118552586 @default.
- W2043304400 hasConcept C126322002 @default.
- W2043304400 hasConcept C142853389 @default.
- W2043304400 hasConcept C15744967 @default.
- W2043304400 hasConcept C170493617 @default.
- W2043304400 hasConcept C2776412080 @default.
- W2043304400 hasConcept C2778976297 @default.
- W2043304400 hasConcept C2780864610 @default.
- W2043304400 hasConcept C542102704 @default.
- W2043304400 hasConcept C71924100 @default.
- W2043304400 hasConcept C98274493 @default.
- W2043304400 hasConceptScore W2043304400C118303440 @default.
- W2043304400 hasConceptScore W2043304400C118552586 @default.
- W2043304400 hasConceptScore W2043304400C126322002 @default.
- W2043304400 hasConceptScore W2043304400C142853389 @default.
- W2043304400 hasConceptScore W2043304400C15744967 @default.
- W2043304400 hasConceptScore W2043304400C170493617 @default.
- W2043304400 hasConceptScore W2043304400C2776412080 @default.
- W2043304400 hasConceptScore W2043304400C2778976297 @default.
- W2043304400 hasConceptScore W2043304400C2780864610 @default.
- W2043304400 hasConceptScore W2043304400C542102704 @default.
- W2043304400 hasConceptScore W2043304400C71924100 @default.
- W2043304400 hasConceptScore W2043304400C98274493 @default.
- W2043304400 hasIssue "2-3" @default.
- W2043304400 hasLocation W20433044001 @default.
- W2043304400 hasLocation W20433044002 @default.
- W2043304400 hasOpenAccess W2043304400 @default.
- W2043304400 hasPrimaryLocation W20433044001 @default.
- W2043304400 hasRelatedWork W1551052972 @default.
- W2043304400 hasRelatedWork W1556261663 @default.
- W2043304400 hasRelatedWork W2274792035 @default.
- W2043304400 hasRelatedWork W2370458311 @default.
- W2043304400 hasRelatedWork W2372091399 @default.
- W2043304400 hasRelatedWork W2478399397 @default.
- W2043304400 hasRelatedWork W3080081859 @default.
- W2043304400 hasRelatedWork W4205148551 @default.
- W2043304400 hasRelatedWork W4210998453 @default.
- W2043304400 hasRelatedWork W4245148164 @default.
- W2043304400 hasVolume "66" @default.
- W2043304400 isParatext "false" @default.
- W2043304400 isRetracted "false" @default.
- W2043304400 magId "2043304400" @default.
- W2043304400 workType "article" @default.