FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043352014> ?p ?o ?g. }

• W2043352014 endingPage "158" @default.
• W2043352014 startingPage "145" @default.
• W2043352014 abstract "Psychological, endocrine and immune parameters were measured over a 6-month period in 14 healthy subjects who underwent an unpredictable acute emotional stress (e.g. sudden death of a loved one) compared with 14 controls who did not. Probands were profoundly stressed as assessed 10 days after bereavement by their scores on the Hamilton Rating Scales of Anxiety and Depression, adrenocorticotropin and cortisol plasma concentrations, and non-suppression in response to dexamethasone. Functional alterations of immune parameters, such as responsiveness of peripheral blood lymphocytes to mitogens, were found 40 days after bereavement. Despite a normal number of circulating lymphocyte subsets, the functional activity of natural killer (NK) cells was markedly reduced at day 40. Changes in the intracellular concentration of beta-endorphin in peripheral blood mononuclear cells correlated with anxiety and depression scores. Controls showed no changes in psychometric, endocrine and immune measures during the 6-month study. Cluster analysis revealed two groups of bereaved subjects with different patterns of immune and endocrine changes: (1) Five subjects, characterized by harm-avoidant temperament and long-lasting dysphoric mood, showed reduced responsiveness of peripheral blood lymphocytes to mitogens, decreased NK cell activity and non-suppression in response to dexamethasone that persisted for 6 months. (2) Nine subjects showed significant changes only during the early phase after bereavement. Our data suggest that the immunological consequences of stress do not simply overlap with psychological and endocrine alterations, and are particularly severe and long-lasting in a subgroup of subjects, indicating the importance of individual variability in the capacity to cope with stress." @default.
• W2043352014 created "2016-06-24" @default.
• W2043352014 creator A5000553265 @default.
• W2043352014 creator A5001779495 @default.
• W2043352014 creator A5067038903 @default.
• W2043352014 creator A5068597337 @default.
• W2043352014 creator A5071885471 @default.
• W2043352014 creator A5078302741 @default.
• W2043352014 creator A5081086372 @default.
• W2043352014 creator A5082929777 @default.
• W2043352014 creator A5088952659 @default.
• W2043352014 date "2003-12-01" @default.
• W2043352014 modified "2023-10-14" @default.
• W2043352014 title "Long-term immune-endocrine effects of bereavement: relationships with anxiety levels and mood" @default.
• W2043352014 cites W101526498 @default.
• W2043352014 cites W1694830854 @default.
• W2043352014 cites W1775749144 @default.
• W2043352014 cites W1968248096 @default.
• W2043352014 cites W1970621701 @default.
• W2043352014 cites W1979180489 @default.
• W2043352014 cites W1979845723 @default.
• W2043352014 cites W1981165220 @default.
• W2043352014 cites W1983274064 @default.
• W2043352014 cites W1985223370 @default.
• W2043352014 cites W1991903108 @default.
• W2043352014 cites W1993688323 @default.
• W2043352014 cites W1994427478 @default.
• W2043352014 cites W1994932307 @default.
• W2043352014 cites W2003011144 @default.
• W2043352014 cites W2011700933 @default.
• W2043352014 cites W2016767581 @default.
• W2043352014 cites W2033538629 @default.
• W2043352014 cites W2034525169 @default.
• W2043352014 cites W2035317071 @default.
• W2043352014 cites W2044472180 @default.
• W2043352014 cites W2056151767 @default.
• W2043352014 cites W2068282347 @default.
• W2043352014 cites W2076832092 @default.
• W2043352014 cites W2081101063 @default.
• W2043352014 cites W2082179949 @default.
• W2043352014 cites W2087611208 @default.
• W2043352014 cites W2088740471 @default.
• W2043352014 cites W2091482735 @default.
• W2043352014 cites W2093115528 @default.
• W2043352014 cites W2099365033 @default.
• W2043352014 cites W2110634897 @default.
• W2043352014 cites W2114613490 @default.
• W2043352014 cites W2125110865 @default.
• W2043352014 cites W2135372888 @default.
• W2043352014 cites W2153661139 @default.
• W2043352014 cites W2160070901 @default.
• W2043352014 cites W2166510636 @default.
• W2043352014 cites W2166734693 @default.
• W2043352014 cites W2169135431 @default.
• W2043352014 cites W2319413353 @default.
• W2043352014 cites W2333165672 @default.
• W2043352014 cites W2404312388 @default.
• W2043352014 cites W3502285 @default.
• W2043352014 doi "https://doi.org/10.1016/s0165-1781(03)00255-5" @default.
• W2043352014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14656449" @default.
• W2043352014 hasPublicationYear "2003" @default.
• W2043352014 type Work @default.
• W2043352014 sameAs 2043352014 @default.
• W2043352014 citedByCount "95" @default.
• W2043352014 countsByYear W20433520142012 @default.
• W2043352014 countsByYear W20433520142013 @default.
• W2043352014 countsByYear W20433520142014 @default.
• W2043352014 countsByYear W20433520142015 @default.
• W2043352014 countsByYear W20433520142016 @default.
• W2043352014 countsByYear W20433520142017 @default.
• W2043352014 countsByYear W20433520142018 @default.
• W2043352014 countsByYear W20433520142019 @default.
• W2043352014 countsByYear W20433520142020 @default.
• W2043352014 countsByYear W20433520142021 @default.
• W2043352014 countsByYear W20433520142022 @default.
• W2043352014 countsByYear W20433520142023 @default.
• W2043352014 crossrefType "journal-article" @default.
• W2043352014 hasAuthorship W2043352014A5000553265 @default.
• W2043352014 hasAuthorship W2043352014A5001779495 @default.
• W2043352014 hasAuthorship W2043352014A5067038903 @default.
• W2043352014 hasAuthorship W2043352014A5068597337 @default.
• W2043352014 hasAuthorship W2043352014A5071885471 @default.
• W2043352014 hasAuthorship W2043352014A5078302741 @default.
• W2043352014 hasAuthorship W2043352014A5081086372 @default.
• W2043352014 hasAuthorship W2043352014A5082929777 @default.
• W2043352014 hasAuthorship W2043352014A5088952659 @default.
• W2043352014 hasConcept C118552586 @default.
• W2043352014 hasConcept C126322002 @default.
• W2043352014 hasConcept C134018914 @default.
• W2043352014 hasConcept C137061746 @default.
• W2043352014 hasConcept C139719470 @default.
• W2043352014 hasConcept C15744967 @default.
• W2043352014 hasConcept C162324750 @default.
• W2043352014 hasConcept C202751555 @default.
• W2043352014 hasConcept C203014093 @default.
• W2043352014 hasConcept C2776867660 @default.
• W2043352014 hasConcept C2777761686 @default.
• W2043352014 hasConcept C2780733359 @default.

• next