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• W2043361871 abstract "Annals of the New York Academy of SciencesVolume 432, Issue 1 p. 17-30 Full Access Demonstration of the Mechanisms for Arrhythmias in Experimental Animalsa BRIAN F. HOFFMAN, BRIAN F. HOFFMAN Department of Pharmacology College of Physicians & Surgeons Columbia University New York, New York 10032Search for more papers by this authorKENNETH H. DANGMAN, KENNETH H. DANGMAN Department of Pharmacology College of Physicians & Surgeons Columbia University New York, New York 10032Search for more papers by this author BRIAN F. HOFFMAN, BRIAN F. HOFFMAN Department of Pharmacology College of Physicians & Surgeons Columbia University New York, New York 10032Search for more papers by this authorKENNETH H. DANGMAN, KENNETH H. DANGMAN Department of Pharmacology College of Physicians & Surgeons Columbia University New York, New York 10032Search for more papers by this author First published: December 1984 https://doi.org/10.1111/j.1749-6632.1984.tb14505.x a Original studies were supported in part by Grants HL-08508, HL-12738, and HL 24354 from the National Heart, Lung and Blood Institute of the National Institutes of Health. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Hoffman, B. F. & M. R. Rosen. 1981. Cellular mechanisms for cardiac arrhythmias. Circ. Res. 49: 69–83. 2 Cranefield, P. F. 1975. The Slow Response and Cardiac Arrhythmias. Futura Press. Mt. Kisco , NY . 3 Cranefield, P. F. 1977. Action potentials, afterpotentials and arrhythmias. Circ. Res. 41: 415–423. 4 Wit, A. L., B. F. Hoffman & P. F. Cranefield. 1972. Slow conduction and reentry in the ventricular conducting system. I. Return extrasystole in canine Purkinje fibers. Circ. Res. 30: 1–10. 5 Antzelevitch, C., J. Jalife & G. K. Moe. 1980. Characteristics of reflection as a mechanism of reentrant arrhythmias and its relationship to parasystole. Circulation 61: 182–191. 6 Mines, G. R. 1914. On circulating excitations in heart muscle and their possible relation to tachycardia and fibrillation. Trans. R. Soc. Can. Ser. 3, Sect IV 8: 43–52. 7 Garrey, W. E. 1914. The nature of fibrillary contraction of the heart. Its relation to tissue mass and form. Am. J. Physiol. 33: 397–414. 8 Lewis, T., et al. 19181921. Observations upon flutter and fibrillation. Parts I-IX. Heart 7: 127-130, 191-346; 8: 37–58, 83–228. 9 Rosenblueth, A. & J. Garcia Ramos. 1947. Studies on flutter and fibrillation. II. The influence of artificial obstacles on experimental auricular flutter. Am. Heart J. 33: 677–684. 10 Janse, M. J., F. J. L. Van Capelle, G. E. Freud & D. Durrer. 1971. Circus movement within the A-V node as a basis for supraventricular tachycardia as shown by multiple microelectrode recordings in the isolated rabbit heart. Circ. Res. 28: 403–414. 11 Bigger, J. T., Jr., & B. N. Goldreyer. 1970. The mechanism of paroxysmal supra-ventricular tachycardia in man. Circulation 42: 673–688. 12 Kosowsky, B. D., J. I. Haft, E. Stein & A. N. Damato. 1968. The effects of digitalis on atrioventricular conduction in man. Am. Heart J. 75: 736–742. 13 Lyons, C. J. & M. J. Burgess. 1979. Demonstration of re-entry within the canine specialized conduction system. Am. Heart J. 98: 595–603. 14 Janse, M. J. J., F. J. L. Van Capelle, H. Morsink, et al. 1980. Flow of “injury” current and patterns of excitation during early ventricular arrhythmias in acute regional myocardial ischemia in isolated porcine and canine hearts: evidence for two different arrhythmogenic mechanisms. Circ. Res. 47: 151–165. 15 Wit, A. L., M. A. Allessie, F. I. M. Bonke, W. Lammers, J. Smeets & J. J. Fenoglio, Jr. 1982. Electrophysiologic mapping to determine the mechanism of experimental ventricular tachycardia initiated by premature impulses. Am. J. Cardiol. 49: 166–185. 16 Horowitz, L. N., M. E. Josephson & A. H. Harken. 1980. Epicardial and endocardial activation during sustained ventricular tachycardia in man. Circulation 61: 1227–1238. 17 Allessie, M. A., F. I. M. Bonke & F. J. G. Schopman. 1977. The “leading circle” concept: A new model of circus movement in cardiac tissue without the involvement of an anatomical obstacle. Circ. Res. 41: 9–19. 18 Boyden, P. A. & B. F. Hoffman. 1981. The effects on atrial electrophysiology and structure of surgically induced right atrial enlargement in dogs. Circ. Res. 49: 1319–1331. 19 Frame, L. H., R. L. Page, P. A. Boyden & B. F. Hoffman. 1983. A right atrial incision that stabilizes reentry around the tricuspid ring in dogs. Circulation 48(4): III-361. 20 Frame, L. H., R. L. Page, & B. F. Hoffman. 1983. Characterization of a model for reentrant excitation around a fixed barrier. Circulation 48(4): III-219. 21 Wit, A. L., P. F. Cranefield & B. F. Hoffman. 1972. Slow conduction and reentry in the ventricular conducting system. II. Single and sustained circus movement in networks of canine and bovine Purkinje fibers. Circ. Res. 30: 11–22. 22 Wit, A. L. & P. F. Cranefield. 1978. Reentrant excitation as a cause of cardiac arrhythmias. Am. J. Physiol. 235: H1–H17. 23 Hoffman, B. F. & K. H. Dangman. 1982. Are arrhythmias caused by automatic impulse generation? In The Symposium on Normal and Abnormal Conduction of the Heart Beat. A. Paes de Carvalho, B. F. Hoffman & M. Lieberman, Eds.: 429–448. Futura Press Mt. Kisco , NY . 24 Cramer, M., M. Siegal, J. T. Bigger & B. F. Hoffman. 1977. Characteristics of extracellular potentials from the sinoatrial pacemaker of the rabbit heart. Circ. Res. 41: 292–300. 25 Hariman, R. J., B. F. Hoffman & R. E. Naylor. 1980. Electrical activity from the sinus node region in conscious dogs. Circ. Res. 47: 775–791. 26 Cramer, M., R. J. Hariman, R. Boxer, & B. F. Hoffman. 1978. Electrograms from the canine sinoatrial pacemaker recorded in vitro and in situ. Am. J. Cardiol. 42: 939–946. 27 Hariman, R. J., E. Krongrad, R. A. Boxer, M. B. Weiss, C. N. Steeg & B. F. Hoffman. 1980. A method for recording electrical activity of the sinoatrial node and automatic atrial foci during cardiac catheterization in humans. Am. J. Cardiol. 45: 775–780. 28 Reiffel, J. A., E. Gang, I. Gliklich, M. B. Weiss, J. C. Davis, J. N. Patton & J. T. Bigger, Jr: 1980. The human sinus node electrogram: A transvenous catheter technique and a comparison of directly measured and indirectly estimated sinoatrial conduction time in adults. Circulation 62: 1324–1334. 29 Hariman, R. J., W. B. Gough, J. A. C. Gomes & N. El-Sherif. 1983. Recording of diastolic slope in a canine model of automatic and unifocal ventricular tachycardia. J. Am. Coll. Cardiol. 1: 731. 30 Hariman, R. J. & C. M. Chen. 1983. Recording of diastolic slope from the junctional area in dogs with junctional rhythm. Circulation 68: 636–643. 31 Dangman, K. H. & B. F. Hoffman. 1983. Studies on overdrive stimulation of canine cardiac Purkinje fibers: Maximal diastolic potential as a determinant of the response. J. Am. Coll. Cardiol. 2: 1183–1190. 32 Vassalle, M. 1977. The relationship among cardiac pacemakers. Overdrive suppression. Circ. Res. 41: 269–277. 33 Bigger, J. T., Jr., & B. F. Hoffman. 1980. Antiarrhythmic drugs. In The Pharmacological Basis of Therapeutics. A. G. Gilman, & L. S. Goodman & A. Gilman, Eds.: 761–792. Macmillan New York , NY . 34 Dangman, K. H. & B. F. Hoffman. 1980. Effects of nifedipine on electrical activity of cardiac cells. Am. J. Cardiol. 46: 1059–1067. 35 Dangman, K. H. & B. F. Hoffman. 1981. In vivo and in vitro antiarrhythmic and arrhythmogenic effects of N-acetyl procainamide. J. Pharmacol. Exp. Ther. 217: 851–862. 36 Ilvento, J. P., J. Provet, P. Danilo & M. R. Rosen. 1982. Fast and slow idioventricular rhythms in the canine heart: A study of their mechanism using antiarrhythmic drugs and electrophysiologic testing. Am. J. Cardiol. 49: 1909–1916. 37 Seegers, M. 1940. La réaction repetitive du coeur. C. R. Soc. Biol. 133: 460–461. 38 Seegers, M. 1940. L'accommodation du rythme cardiaque. Arch. Int. Physiol. 50 277–308. 39 Seegers, M. 1941. Le rôle des potentiels tardifs du coeur. Mem. Acad. R. Med. Belg (series II) 1: 1–30. 40 Seegers, M. 1947. Le battement auto-entretenu du coeur. Arch. Int. Pharmacodyn 75: 144–156. 41 Bozler, E. 1943. The initiation of impulses in cardiac muscle. Am. J. Physiol. 138: 273–282. 42 Scherf, D. & A. Schott. 1953. Extrasystoles and Allied Arrhythmias. Heinemann Medical Books. Melbourne , Australia . 43 Rosen, M. R., C. Fisch, B. F. Hoffman, P. Danilo, Jr., D. E. Lovelace & S. B. Knoebel. 1980. Can accelerated atrioventricular junctional escape rhythms be explained by delayed afterdepolarizations? Am. J. Cardiol. 45: 1272–1284. 44 El-Sherif, N., W. B. Gough, R. H. Zeiler & R. Mehra. 1983. Triggered ventricular rhythms in 1-day-old myocardial infarction in the dog. Circ. Res. 52: 566–579. 45 Brachmann, J., B. J. Scherlag, L. V. Rosenshtraukh & R. Lazzara. 1983. Bradycardia-dependent triggered activity: Relevance to drug-induced multiform ventricular tachycardia. Circulation 68: 846–856. 46 Cramer, M., L. Mary-Rabine, A. Wit & B. F. Hoffman. 1977. Extracellular potentials produced by delayed afterdepolarizations. Circulation 56 (Suppl II): 302. Volume432, Issue1Clinical Pharmacology of Cardiac Antiarrhythmic Agents: Classical and Current ConceptsDecember 1984Pages 17-30 ReferencesRelatedInformation" @default.
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