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• W2043375896 abstract "Abstract Previous studies of clinical nutrition report diverse findings. Differences in design, with respect to type and number of patients, randomisation, alternatives, time-span, measured variables as well as shortcomings in statistical analysis, provide an uncertain basis on which to draw firm and generally accepted conclusions. In order to show the usefulness of the cost-benefit approach three strategies for reducing the incidence of nutrition-associated complications were compared: (a) provide all patients with nutritional support, (b) support no patients, or (c) test first-support only ‘high-risk’ patients. Based on some realistic assumptions, the study concludes that the third strategy will minimise both complications and costs, if the incidence of nutrition-related complications are between 12 and 38%. These results depend, however, also on the sensitivity and specificity of the test procedure; the efficacy of parenteral nutrition and the incidence of iatrogenic complications; and the costs of nutritional support, iatrogenic complications, and test procedure. The results are all based on secondary data not specifically suited to economic analysis, so they are to some degree only tentative. Ideally, both clinical and economic data should be collected simultaneously in well designed and properly performed randomised controlled trials." @default.
• W2043375896 created "2016-06-24" @default.
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• W2043375896 date "1987-08-01" @default.
• W2043375896 modified "2023-10-18" @default.
• W2043375896 title "Clinical and economic aspects on nutritional supply" @default.
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• W2043375896 doi "https://doi.org/10.1016/0261-5614(87)90055-0" @default.
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