FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043419319> ?p ?o ?g. }

• W2043419319 endingPage "1459" @default.
• W2043419319 startingPage "1450" @default.
• W2043419319 abstract "Different glucose transport systems are examined for their impact on phosphoenolpyruvate availability as reflected by the yields of 3-dehydroshikimic acid and byproducts 3-deoxy-d-arabino-heptulosonic acid, 3-dehydroquinic acid, and gallic acid synthesized by Escherichia coli from glucose. 3-Dehydroshikimic acid is an advanced shikimate pathway intermediate in the syntheses of a spectrum of commodity, pseudocommodity, and fine chemicals. All constructs carried plasmid aroF(FBR) and tktA inserts encoding, respectively, a feedback-insensitive isozyme of 3-deoxy-d-arabino-heptulosonic acid 7-phosphate synthase and transketolase. Reliance on the native E. coli phosphoenolpyruvate:carbohydrate phosphotransferase system for glucose transport led in 48 h to the synthesis of 3-dehydroshikimic acid (49 g/L) and shikimate pathway byproducts in a total yield of 33% (mol/mol). Use of heterologously expressed Zymomonas mobilis glf-encoded glucose facilitator and glk-encoded glucokinase resulted in the synthesis in 48 h of 3-dehydroshikimic acid (60 g/L) and shikimate pathway byproducts in a total yield of 41% (mol/mol). Recruitment of native E. coli galP-encoded galactose permease for glucose transport required 60 h to synthesize 3-dehydroshikimic acid (60 g/L) and shikimate pathway byproducts in a total yield of 43% (mol/mol). Direct comparison of the impact of altered glucose transport on the yields of shikimate pathway products synthesized by E. coli has been previously hampered by different experimental designs and culturing conditions. In this study, the same product and byproduct mixture synthesized by E. coli constructs derived from the same progenitor strain is used to compare strategies for increasing phosphoenolpyruvate availability. Constructs are cultured under the same set of fermentor-controlled conditions." @default.
• W2043419319 created "2016-06-24" @default.
• W2043419319 creator A5019147969 @default.
• W2043419319 creator A5051363890 @default.
• W2043419319 creator A5054854652 @default.
• W2043419319 creator A5058727375 @default.
• W2043419319 date "2003-01-01" @default.
• W2043419319 modified "2023-10-14" @default.
• W2043419319 title "Altered Glucose Transport and Shikimate Pathway Product Yields in E. coli" @default.
• W2043419319 cites W1520001214 @default.
• W2043419319 cites W1550655865 @default.
• W2043419319 cites W1585571745 @default.
• W2043419319 cites W1588681068 @default.
• W2043419319 cites W1592212731 @default.
• W2043419319 cites W1861520129 @default.
• W2043419319 cites W1926186550 @default.
• W2043419319 cites W1973244479 @default.
• W2043419319 cites W1976095793 @default.
• W2043419319 cites W1983595497 @default.
• W2043419319 cites W1988431706 @default.
• W2043419319 cites W1989259110 @default.
• W2043419319 cites W1989708883 @default.
• W2043419319 cites W1996472556 @default.
• W2043419319 cites W1997562369 @default.
• W2043419319 cites W1998781224 @default.
• W2043419319 cites W2000487125 @default.
• W2043419319 cites W2001007760 @default.
• W2043419319 cites W2003721913 @default.
• W2043419319 cites W2004375887 @default.
• W2043419319 cites W2011072729 @default.
• W2043419319 cites W2012493190 @default.
• W2043419319 cites W2029491068 @default.
• W2043419319 cites W2036088822 @default.
• W2043419319 cites W2044318184 @default.
• W2043419319 cites W2046855048 @default.
• W2043419319 cites W2051577230 @default.
• W2043419319 cites W2057893359 @default.
• W2043419319 cites W2064443518 @default.
• W2043419319 cites W2071622896 @default.
• W2043419319 cites W2084056034 @default.
• W2043419319 cites W2094123239 @default.
• W2043419319 cites W2097311150 @default.
• W2043419319 cites W2131398725 @default.
• W2043419319 cites W2139530917 @default.
• W2043419319 cites W2148063387 @default.
• W2043419319 cites W2167153673 @default.
• W2043419319 cites W2949459453 @default.
• W2043419319 cites W4293247451 @default.
• W2043419319 cites W4323285386 @default.
• W2043419319 doi "https://doi.org/10.1021/bp0340584" @default.
• W2043419319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14524706" @default.
• W2043419319 hasPublicationYear "2003" @default.
• W2043419319 type Work @default.
• W2043419319 sameAs 2043419319 @default.
• W2043419319 citedByCount "63" @default.
• W2043419319 countsByYear W20434193192012 @default.
• W2043419319 countsByYear W20434193192013 @default.
• W2043419319 countsByYear W20434193192014 @default.
• W2043419319 countsByYear W20434193192015 @default.
• W2043419319 countsByYear W20434193192016 @default.
• W2043419319 countsByYear W20434193192017 @default.
• W2043419319 countsByYear W20434193192018 @default.
• W2043419319 countsByYear W20434193192019 @default.
• W2043419319 countsByYear W20434193192020 @default.
• W2043419319 countsByYear W20434193192021 @default.
• W2043419319 countsByYear W20434193192023 @default.
• W2043419319 crossrefType "journal-article" @default.
• W2043419319 hasAuthorship W2043419319A5019147969 @default.
• W2043419319 hasAuthorship W2043419319A5051363890 @default.
• W2043419319 hasAuthorship W2043419319A5054854652 @default.
• W2043419319 hasAuthorship W2043419319A5058727375 @default.
• W2043419319 hasConcept C100544194 @default.
• W2043419319 hasConcept C103432212 @default.
• W2043419319 hasConcept C104317684 @default.
• W2043419319 hasConcept C143937172 @default.
• W2043419319 hasConcept C161790260 @default.
• W2043419319 hasConcept C181199279 @default.
• W2043419319 hasConcept C185592680 @default.
• W2043419319 hasConcept C190114821 @default.
• W2043419319 hasConcept C2778255928 @default.
• W2043419319 hasConcept C2779227428 @default.
• W2043419319 hasConcept C2780604136 @default.
• W2043419319 hasConcept C2780604391 @default.
• W2043419319 hasConcept C2781440633 @default.
• W2043419319 hasConcept C45656491 @default.
• W2043419319 hasConcept C547475151 @default.
• W2043419319 hasConcept C553450214 @default.
• W2043419319 hasConcept C55493867 @default.
• W2043419319 hasConcept C65183824 @default.
• W2043419319 hasConceptScore W2043419319C100544194 @default.
• W2043419319 hasConceptScore W2043419319C103432212 @default.
• W2043419319 hasConceptScore W2043419319C104317684 @default.
• W2043419319 hasConceptScore W2043419319C143937172 @default.
• W2043419319 hasConceptScore W2043419319C161790260 @default.
• W2043419319 hasConceptScore W2043419319C181199279 @default.
• W2043419319 hasConceptScore W2043419319C185592680 @default.
• W2043419319 hasConceptScore W2043419319C190114821 @default.
• W2043419319 hasConceptScore W2043419319C2778255928 @default.

• next