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- W2043459780 abstract "The parallel synthesis of O-aryloxyamines remains an unfulfilled need in the field of medicinal chemistry and fragment-based approaches. To fill this gap a solution-phase two-step process based on (1) a copper-catalyzed cross-coupling of aryl boronic acids with a fluorous tagged N-hydroxyphthalimide, and (2) a supported aminolysis was designed and optimized using Taguchi’s method. A library of O-aryloxyamines was synthesized in high yields with high purity and diversity." @default.
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- W2043459780 date "2010-07-22" @default.
- W2043459780 modified "2023-09-25" @default.
- W2043459780 title "Fluorous Tagged <i>N</i>-Hydroxy Phthalimide for the Parallel Synthesis of <i>O</i>-Aryloxyamines" @default.
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- W2043459780 doi "https://doi.org/10.1021/cc100098v" @default.
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