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- W2043462668 abstract "Although the field of pharmacogenetics has existed for decades, practioners have been slow to implement pharmacogenetic testing in clinical care. Numerous publications describe the barriers to clinical implementation of pharmacogenetics. Recently, several freely available resources have been developed to help address these barriers. In this review, we discuss current programs that use preemptive genotyping to optimize the pharmacotherapy of patients. Array-based preemptive testing includes a large number of relevant pharmacogenes that impact multiple high-risk drugs. Using a preemptive approach allows genotyping results to be available prior to any prescribing decision so that genomic variation may be considered as an inherent patient characteristic in the planning of therapy. This review describes the common elements among programs that have implemented preemptive genotyping and highlights key processes for implementation, including clinical decision support." @default.
- W2043462668 created "2016-06-24" @default.
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- W2043462668 date "2015-01-06" @default.
- W2043462668 modified "2023-10-11" @default.
- W2043462668 title "Preemptive Clinical Pharmacogenetics Implementation: Current Programs in Five US Medical Centers" @default.
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- W2043462668 doi "https://doi.org/10.1146/annurev-pharmtox-010814-124835" @default.
- W2043462668 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4607278" @default.
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- W2043462668 hasPublicationYear "2015" @default.
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