FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043482568> ?p ?o ?g. }

• W2043482568 endingPage "444" @default.
• W2043482568 startingPage "438" @default.
• W2043482568 abstract "Purpose of review The fibrinolytic system plays a key role in the regulation of hemostasis and thrombosis; however, it also has multiple pleiotropic effects. In this review, we examine the studies that investigated the role of the plasminogen activator system and its inhibitors outside the context of clot lysis. Recent findings Activators of plasminogen, plasminogen receptors, and inhibitors of plasminogen activation all play a role in the proliferation, migration, and metastasis of tumor cells in many cancer types and may serve as prognostic and diagnostic markers. The plasminogen activator system is also involved in the pathogenesis and severity of several inflammatory diseases, including sepsis, metabolic disease, arthritis, and airway disease. A study on the use of tissue plasminogen activator (tPA) following cerebrovascular events demonstrates that tPA also plays important roles in the pathogenesis of stroke and affects the long-term outcomes. Summary Current evidence suggests an association between the plasminogen activator system and its inhibitors in a variety of malignant and inflammatory states. Newly discovered roles for plasminogen activators and plasminogen activator inhibitors in these diseases provide novel targets for future therapeutic development. Additionally, the newly characterized regulation of the plasminogen activator system by endogenous microRNAs provides new insight into the physiological role of this system and its role in disease." @default.
• W2043482568 created "2016-06-24" @default.
• W2043482568 creator A5054664615 @default.
• W2043482568 creator A5073856682 @default.
• W2043482568 date "2014-09-01" @default.
• W2043482568 modified "2023-10-17" @default.
• W2043482568 title "Emerging pathophysiological roles for fibrinolysis" @default.
• W2043482568 cites W1599132736 @default.
• W2043482568 cites W1789876634 @default.
• W2043482568 cites W1864629760 @default.
• W2043482568 cites W1971468895 @default.
• W2043482568 cites W1976100378 @default.
• W2043482568 cites W1976729214 @default.
• W2043482568 cites W1978346341 @default.
• W2043482568 cites W1987718271 @default.
• W2043482568 cites W1988076663 @default.
• W2043482568 cites W1988593940 @default.
• W2043482568 cites W1992049490 @default.
• W2043482568 cites W1995541763 @default.
• W2043482568 cites W2001323541 @default.
• W2043482568 cites W2004774935 @default.
• W2043482568 cites W2010673416 @default.
• W2043482568 cites W2023973361 @default.
• W2043482568 cites W2033647971 @default.
• W2043482568 cites W2037429771 @default.
• W2043482568 cites W2047923753 @default.
• W2043482568 cites W2054542782 @default.
• W2043482568 cites W2057945141 @default.
• W2043482568 cites W2058689904 @default.
• W2043482568 cites W2067208148 @default.
• W2043482568 cites W2075437119 @default.
• W2043482568 cites W2077976088 @default.
• W2043482568 cites W2080285768 @default.
• W2043482568 cites W2082711424 @default.
• W2043482568 cites W2100215246 @default.
• W2043482568 cites W2101557021 @default.
• W2043482568 cites W2106033318 @default.
• W2043482568 cites W2109884554 @default.
• W2043482568 cites W2113247475 @default.
• W2043482568 cites W2118659300 @default.
• W2043482568 cites W2124158043 @default.
• W2043482568 cites W2137672315 @default.
• W2043482568 cites W2147494302 @default.
• W2043482568 cites W2155199341 @default.
• W2043482568 cites W2168144042 @default.
• W2043482568 cites W2171420082 @default.
• W2043482568 cites W2171781946 @default.
• W2043482568 cites W2332695270 @default.
• W2043482568 cites W1995327227 @default.
• W2043482568 doi "https://doi.org/10.1097/moh.0000000000000068" @default.
• W2043482568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24977437" @default.
• W2043482568 hasPublicationYear "2014" @default.
• W2043482568 type Work @default.
• W2043482568 sameAs 2043482568 @default.
• W2043482568 citedByCount "13" @default.
• W2043482568 countsByYear W20434825682014 @default.
• W2043482568 countsByYear W20434825682015 @default.
• W2043482568 countsByYear W20434825682016 @default.
• W2043482568 countsByYear W20434825682017 @default.
• W2043482568 countsByYear W20434825682019 @default.
• W2043482568 countsByYear W20434825682020 @default.
• W2043482568 countsByYear W20434825682022 @default.
• W2043482568 countsByYear W20434825682023 @default.
• W2043482568 crossrefType "journal-article" @default.
• W2043482568 hasAuthorship W2043482568A5054664615 @default.
• W2043482568 hasAuthorship W2043482568A5073856682 @default.
• W2043482568 hasConcept C126322002 @default.
• W2043482568 hasConcept C203014093 @default.
• W2043482568 hasConcept C2776572282 @default.
• W2043482568 hasConcept C2776825266 @default.
• W2043482568 hasConcept C2779679481 @default.
• W2043482568 hasConcept C2780675426 @default.
• W2043482568 hasConcept C2780942790 @default.
• W2043482568 hasConcept C502942594 @default.
• W2043482568 hasConcept C60644358 @default.
• W2043482568 hasConcept C71924100 @default.
• W2043482568 hasConcept C86803240 @default.
• W2043482568 hasConceptScore W2043482568C126322002 @default.
• W2043482568 hasConceptScore W2043482568C203014093 @default.
• W2043482568 hasConceptScore W2043482568C2776572282 @default.
• W2043482568 hasConceptScore W2043482568C2776825266 @default.
• W2043482568 hasConceptScore W2043482568C2779679481 @default.
• W2043482568 hasConceptScore W2043482568C2780675426 @default.
• W2043482568 hasConceptScore W2043482568C2780942790 @default.
• W2043482568 hasConceptScore W2043482568C502942594 @default.
• W2043482568 hasConceptScore W2043482568C60644358 @default.
• W2043482568 hasConceptScore W2043482568C71924100 @default.
• W2043482568 hasConceptScore W2043482568C86803240 @default.
• W2043482568 hasIssue "5" @default.
• W2043482568 hasLocation W20434825681 @default.
• W2043482568 hasLocation W20434825682 @default.
• W2043482568 hasOpenAccess W2043482568 @default.
• W2043482568 hasPrimaryLocation W20434825681 @default.
• W2043482568 hasRelatedWork W1928726551 @default.
• W2043482568 hasRelatedWork W1995024643 @default.
• W2043482568 hasRelatedWork W2010925764 @default.
• W2043482568 hasRelatedWork W2319089591 @default.
• W2043482568 hasRelatedWork W2368907777 @default.

• next