Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043508769> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2043508769 endingPage "142" @default.
- W2043508769 startingPage "139" @default.
- W2043508769 abstract "The serum amyloid A (SAA) proteins are a polymorphic family of apolipoproteins associated with high-density lipoproteins (HDL). Three distinct subfamilies have been identified: (i) a cytokine-induced acute phase subfamily that is hepatically produced and can become the major apolipoprotein on HDL (SAA1, SAA2); (ii) a peripherally produced acute phase SAA3 that is only a minor HDL apolipoprotein; and (iii) a constitutive subfamily (SAA4) that is a minor normal HDL apolipoprotein comprising more than 90% of the SAA during homeostasis. Here we define the structure of theSaa4gene. Similar to other Saa family members, it has four exons and three introns. It is 4588 bp long from the transcription start site to the end of the 3′-untranslated region and is approximately 20% larger than otherSaagenes. We have locatedSaa411 kb upstream fromSaa3and 5 kb downstream fromSaa1,with the pseudogene approximately 1 kb from the 5′ end ofSaa4. Saa4has the same orientation as most otherSaafamily members, with onlySaa2having an opposing orientation. These data promote our understanding of the evolution of theSaafamily. They enhance our ability to develop the mouse as a transgenic and gene deletion model to advance the understanding of the function of these apolipoproteins." @default.
- W2043508769 created "2016-06-24" @default.
- W2043508769 creator A5002466774 @default.
- W2043508769 creator A5017253442 @default.
- W2043508769 creator A5020781568 @default.
- W2043508769 creator A5062190904 @default.
- W2043508769 creator A5066408141 @default.
- W2043508769 creator A5082058844 @default.
- W2043508769 creator A5090860934 @default.
- W2043508769 date "1996-05-01" @default.
- W2043508769 modified "2023-09-27" @default.
- W2043508769 title "Structure of the MouseSaa4Gene and Its Linkage to the Serum Amyloid A Gene Family" @default.
- W2043508769 doi "https://doi.org/10.1006/geno.1996.0253" @default.
- W2043508769 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8661036" @default.
- W2043508769 hasPublicationYear "1996" @default.
- W2043508769 type Work @default.
- W2043508769 sameAs 2043508769 @default.
- W2043508769 citedByCount "29" @default.
- W2043508769 countsByYear W20435087692012 @default.
- W2043508769 countsByYear W20435087692013 @default.
- W2043508769 countsByYear W20435087692014 @default.
- W2043508769 countsByYear W20435087692018 @default.
- W2043508769 countsByYear W20435087692019 @default.
- W2043508769 countsByYear W20435087692020 @default.
- W2043508769 countsByYear W20435087692022 @default.
- W2043508769 countsByYear W20435087692023 @default.
- W2043508769 crossrefType "journal-article" @default.
- W2043508769 hasAuthorship W2043508769A5002466774 @default.
- W2043508769 hasAuthorship W2043508769A5017253442 @default.
- W2043508769 hasAuthorship W2043508769A5020781568 @default.
- W2043508769 hasAuthorship W2043508769A5062190904 @default.
- W2043508769 hasAuthorship W2043508769A5066408141 @default.
- W2043508769 hasAuthorship W2043508769A5082058844 @default.
- W2043508769 hasAuthorship W2043508769A5090860934 @default.
- W2043508769 hasConcept C104317684 @default.
- W2043508769 hasConcept C141231307 @default.
- W2043508769 hasConcept C153911025 @default.
- W2043508769 hasConcept C203014093 @default.
- W2043508769 hasConcept C2776914184 @default.
- W2043508769 hasConcept C2778163477 @default.
- W2043508769 hasConcept C34957205 @default.
- W2043508769 hasConcept C36823959 @default.
- W2043508769 hasConcept C50929876 @default.
- W2043508769 hasConcept C54355233 @default.
- W2043508769 hasConcept C55359608 @default.
- W2043508769 hasConcept C55493867 @default.
- W2043508769 hasConcept C62746215 @default.
- W2043508769 hasConcept C86803240 @default.
- W2043508769 hasConcept C94671646 @default.
- W2043508769 hasConceptScore W2043508769C104317684 @default.
- W2043508769 hasConceptScore W2043508769C141231307 @default.
- W2043508769 hasConceptScore W2043508769C153911025 @default.
- W2043508769 hasConceptScore W2043508769C203014093 @default.
- W2043508769 hasConceptScore W2043508769C2776914184 @default.
- W2043508769 hasConceptScore W2043508769C2778163477 @default.
- W2043508769 hasConceptScore W2043508769C34957205 @default.
- W2043508769 hasConceptScore W2043508769C36823959 @default.
- W2043508769 hasConceptScore W2043508769C50929876 @default.
- W2043508769 hasConceptScore W2043508769C54355233 @default.
- W2043508769 hasConceptScore W2043508769C55359608 @default.
- W2043508769 hasConceptScore W2043508769C55493867 @default.
- W2043508769 hasConceptScore W2043508769C62746215 @default.
- W2043508769 hasConceptScore W2043508769C86803240 @default.
- W2043508769 hasConceptScore W2043508769C94671646 @default.
- W2043508769 hasIssue "1" @default.
- W2043508769 hasLocation W20435087691 @default.
- W2043508769 hasLocation W20435087692 @default.
- W2043508769 hasOpenAccess W2043508769 @default.
- W2043508769 hasPrimaryLocation W20435087691 @default.
- W2043508769 hasRelatedWork W1971010738 @default.
- W2043508769 hasRelatedWork W1999232590 @default.
- W2043508769 hasRelatedWork W2004096242 @default.
- W2043508769 hasRelatedWork W2022764010 @default.
- W2043508769 hasRelatedWork W2033100306 @default.
- W2043508769 hasRelatedWork W2035919360 @default.
- W2043508769 hasRelatedWork W2088901427 @default.
- W2043508769 hasRelatedWork W2092554027 @default.
- W2043508769 hasRelatedWork W2131379448 @default.
- W2043508769 hasRelatedWork W4242521457 @default.
- W2043508769 hasVolume "34" @default.
- W2043508769 isParatext "false" @default.
- W2043508769 isRetracted "false" @default.
- W2043508769 magId "2043508769" @default.
- W2043508769 workType "article" @default.