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• W2043545111 abstract "Various high-mannose-type glycan modifications of dihydrofolate reductase (DHFR) were achieved by ligand-based approach using glycan–methotrexate (MTX) conjugates as tight binding glycan bearing ligands for DHFR. The resulting glycan–MTX conjugates and the corresponding artificial glycoproteins could be useful as oligosaccharide- and glycoprotein-probes to perform quantitative analysis of glycan recognizing protein such as lectins, glycosyltransferases or glycosidases. Moreover, artificial glycoproteins having two different high-mannose-type glycans were developed for the first time by a combination of two different types of glycan modification strategies." @default.
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• W2043545111 date "2006-08-01" @default.
• W2043545111 modified "2023-10-17" @default.
• W2043545111 title "High-mannose-type glycan modifications of dihydrofolate reductase using glycan–methotrexate conjugates" @default.
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• W2043545111 doi "https://doi.org/10.1016/j.bmc.2006.04.001" @default.
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