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• W2043565512 abstract "The proper development and functioning of the vertebrate brain depends on the correct positioning of neuronal precursors which is achieved by the widespread and far-ranging migration of cells from their birthplaces. The vast majority of neuronal precursors use cellular substrates for their migration. Until very recently, it was assumed that these cellular substrates were either glial (glia-mediated or gliophilic migration) or neuronal (neuron-mediated or neurophilic migration) in nature. The widely studied examples of gliophilic and neurophilic migrations in the developing brain are displacement of neuronal precursors along the processes of radial glia in the developing cortex and migration of neurons expressing gonadotropin-releasing hormone (GnRH) along the vomeronasal axons, respectively. Recent data indicate, however, that neuronal precursors might also use blood vessels as a physical substrate for their migration. The vasculature-guided (vasophilic) migration of neuronal precursors has been observed not only under normal conditions, in the healthy brain, but also following strokes. The purpose of this review is to highlight emerging principles and delineate putative mechanisms of vasculature-guided neuronal migration under both normal and pathological conditions." @default.
• W2043565512 created "2016-06-24" @default.
• W2043565512 creator A5091123067 @default.
• W2043565512 date "2009-08-01" @default.
• W2043565512 modified "2023-10-07" @default.
• W2043565512 title "Role of blood vessels in the neuronal migration" @default.
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• W2043565512 doi "https://doi.org/10.1016/j.semcdb.2009.04.006" @default.
• W2043565512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19374951" @default.
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