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• W2043579412 abstract "Differentiated primary rat hepatocyte cultures have been infected with retroviral vectors expressing human hypoxanthine/guanine phosphoribosyltransferase or the transposon Tn5 neomycin-resistance gene. Expression of the markers was detected only after infection of the cells during a short period of cell replication and transient dedifferentiation from days 1 to 5 of culture. Provirus integrated during that period remains fully expressed during the entire subsequent stationary period of culture up to at least 25 days. Selection with the neomycin analogue G418 of cells infected with the neomycin vector led to the appearance of cells with hepatocyte morphology in which newly synthesized albumin was detectable by immunoprecipitation, indicating successful infection of hepatocytes." @default.
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• W2043579412 date "1987-05-01" @default.
• W2043579412 modified "2023-09-25" @default.
• W2043579412 title "Expression of retrovirally transduced genes in primary cultures of adult rat hepatocytes." @default.
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• W2043579412 doi "https://doi.org/10.1073/pnas.84.10.3344" @default.
• W2043579412 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/304866" @default.
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