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- W2043580911 abstract "A compound that could be converted to prostaglandin F2α by mild chemical reduction was formed by human platelets in response to arachidonic acid, collagen, or L-epinephrine. It was present in maximal amounts at about 1 min after addition of arachidonic acid or collagen to platelet-rich plasma. Its initial formation appeared to precede platelet aggregation by these agents and was closely correlated with the release of adenine nucleotides and radioactive 5-hydroxytryptamine from platelets. Moreover, the compound was itself found outside the platelets. This compound is probably an endoperoxide intermediate in prostaglandin biosynthesis and may be a trigger for the platelet release reaction." @default.
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- W2043580911 title "Formation of an Intermediate in Prostaglandin Biosynthesis and Its Association with the Platelet Release Reaction" @default.
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- W2043580911 doi "https://doi.org/10.1172/jci107695" @default.
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