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• W2043602014 abstract "Idiopathic intracranial hypertension (IIH), also known as pseudotumor cerebri or benign intracranial hypertension, is the diagnostic term used for a syndrome defined by modified Dandy criteria [ [1] Smith J.L Whence pseudotumor cerebri?. J. Clin. Neuroophthalmol. 1985; 5: 55-56 PubMed Google Scholar ]. These are: (1)signs and symptoms of increased intracranial pressure, (2)absence of localizing findings on neurological examination, (3)absence of deformity, displacement, or obstruction of the ventricular system and otherwise normal neurodiagnostic studies, except for increased cerebrospinal fluid pressure, (4)awake and alert patient, (5)no other cause of increased intracranial pressure present. Although a clinical picture indistinguishable from IIH may occur because of dural venous thrombosis, the typical MRI from patients with IIH shows no signs of cerebral venous thrombosis. The most widely accepted hypothesis for the cause of raised CSF pressure in IIH is reduced CSF absorption through the arachnoid villi rather than impairment of venous drainage due to cerebral veno-occlusive disease [ 2 Martins A.N Resistance to drainage of cerebrospinal fluid: clinical measurement and significance. J. Neurol. Neurosurg. Psychiatry. 1973; 36: 313-318 Crossref PubMed Scopus (59) Google Scholar , 3 Calabrese V.P Selhorst J.B Harbison J.W CSF infusion test in pseudotumor cerebri. Trans. Am. Neurol. Assoc. 1978; 103: 146-150 PubMed Google Scholar , 4 Janny P Chazal J Colnet G Irthum B Georget A.M Benign intracranial hypertension and disorders of CSF absorption. Surg. Neurol. 1981; 15: 168-174 Abstract Full Text PDF PubMed Scopus (84) Google Scholar , 5 Gjerris F Soelberg Sorensen P Vorstrup S Paulson O.B Intracranial pressure, conductance to cerebrospinal fluid outflow, and cerebral blood flow in patients with benign intracranial hypertension (pseudotumor cerebri). Ann. Neurol. 1985; 17: 158-162 Crossref PubMed Scopus (84) Google Scholar , 6 Malm J Kristensen B Markgren P Ekstedt J CSF hydrodynamics in idiopathic intracranial hypertension: a long-term study. Neurology. 1992; 42: 851-858 Crossref PubMed Google Scholar , 7 Quattrone A Gambardella A Carbone A.M Oliveri R.L Lavano A De Marco E.V et al. A hypofibrinolytic state in overweight patients with cerebral venous thrombosis and isolated intracranial hypertension. J. Neurol. 1999; 246: 1086-1089 Crossref PubMed Scopus (27) Google Scholar ]. Although IIH is a disorder of unknown cause, it develops in different settings without an apparent, common pathogenesis. The occurrence of several reports documenting familial clustering suggested that potential genetic polymorphisms may become clinically manifest after exposure to conditions known to precipitate IIH [ 8 Buchheit W.A Burton C Haag B Shaw D Papilledema and idiopathic intracranial hypertension: a report of a familial occurrence. N. Engl. J. 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Neurol. 1989; 29: 106-108 Crossref PubMed Scopus (22) Google Scholar , 15 Johnston I Morgan M.K A familial coincidence of pseudotumor cerebri and communicating hydrocephalus. Neurosurgery. 1991; 28: 727-729 Crossref PubMed Scopus (18) Google Scholar , 16 Kharode C McAbee G Sherman J Kaufman M Familial intracranial hypertension: report of a case and review of the literature. J. Child. Neurol. 1992; 7: 196-198 Crossref PubMed Scopus (27) Google Scholar , 17 Rogel Ortiz F.J Vera Pedro M Pseudotumor cerebri of familial presentation. Gac. Med. Mex. 1994; 130: 265-268 PubMed Google Scholar , 18 Gardner K Cox T Digre K.B Idiopathic intracranial hypertension associated with tetracycline use in fraternal twins: case reports and review. Neurology. 1995; 45: 6-10 Crossref PubMed Scopus (87) Google Scholar , 19 Salmaggi A Marano R Silvani A Pozzi A de Luca G Familial intracranial hypertension: a case report. Ital. J. Neurol. Sci. 1996; 17: 167-168 Crossref PubMed Scopus (5) Google Scholar , 20 Fujiwara S Sawamura Y Kato T Abe H Katusima H Idiopathic intracranial hypertension in female homozygous twins. J. Neurol. Neurosurg. Psychiatry. 1997; 62: 652-654 Crossref PubMed Scopus (25) Google Scholar , 21 Santinelli R Tolone C Toraldo R Canino G de Simone A D'Avanzo M Familial idiopathic intracranial hypertension with spinal and radicular pain. Arch. Neurol. 1998; 55: 854-856 Crossref PubMed Scopus (20) Google Scholar , 22 Miller N.R Newman N.J Papilledema. in: Miller N.R Newman N.J The essentials: Walsh and Hoyt's Clinical Neuro-Ophthalmology. 5th ed. Williams & Wilkins, Baltimore1999: 166-195 Google Scholar ]." @default.
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• W2043602014 title "Evidence for genetic susceptibility to thrombosis in idiopathic intracranial hypertension" @default.
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• W2043602014 doi "https://doi.org/10.1016/j.thromres.2003.09.030" @default.
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