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• W2043625348 abstract "A growing amount of evidence has suggested that hydrogen sulfide (H 2 S), as a gasotransmitter, is involved in intensive physiological and pathological processes. More and more research groups have found that H 2 S mediates diverse cellular biological functions related to regulating intracellular calcium concentration. These groups have demonstrated the reciprocal interaction between H 2 S and calcium ion channels and transporters, such as L-type calcium channels (LTCC), T-type calcium channels (TTCC), sodium/calcium exchangers (NCX), transient receptor potential (TRP) channels, β -adrenergic receptors, and N-methyl-D-aspartate receptors (NMDAR) in different cells. However, the understanding of the molecular targets and mechanisms is incomplete. Recently, some research groups demonstrated that H 2 S modulates the activity of calcium ion channels through protein S-sulfhydration and polysulfide reactions. In this review, we elucidate that H 2 S controls intracellular calcium homeostasis and the underlying mechanisms." @default.
• W2043625348 created "2016-06-24" @default.
• W2043625348 creator A5007660396 @default.
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• W2043625348 creator A5084688862 @default.
• W2043625348 date "2015-01-01" @default.
• W2043625348 modified "2023-10-16" @default.
• W2043625348 title "Interaction of H_<b>2</b>S with Calcium Permeable Channels and Transporters" @default.
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• W2043625348 doi "https://doi.org/10.1155/2015/323269" @default.
• W2043625348 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4442308" @default.
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• W2043625348 hasPublicationYear "2015" @default.
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