Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043663359> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2043663359 endingPage "98" @default.
- W2043663359 startingPage "89" @default.
- W2043663359 abstract "The synthesis of O-alkylglycerophospho-l-serine analogs is described, which represent a new class of cytostatically active agents based on phospholipids. The new compounds were obtained by conversion of O-alkylglycerophosphoric ester analogs by means of phospholipase D and by condensing O-alkylglycerophosphoric acid analogs with protected l-serine followed by the removal of protective groups of the resulting intermediates. The structure of the O-alkylglycerophospho-l-serines was confirmed by fast atom bombardment mass spectrometry. The compounds were found to inhibit the growth of Ehrlich ascites tumor cells in vitro. Half maximum inhibition was observed at concentrations between 7 and 15 μM. For the 1-O-alkyl-2-methoxy glycerophosphoserine only a higher value (30 μM) was found. With most of the substances tested growth was completely inhibited at a concentration of 40 μM." @default.
- W2043663359 created "2016-06-24" @default.
- W2043663359 creator A5018224101 @default.
- W2043663359 creator A5059409314 @default.
- W2043663359 creator A5074023473 @default.
- W2043663359 creator A5075251959 @default.
- W2043663359 creator A5083765016 @default.
- W2043663359 creator A5089898334 @default.
- W2043663359 date "1990-05-01" @default.
- W2043663359 modified "2023-10-02" @default.
- W2043663359 title "Halo lipids. 10. Synthesis and cytostatic activity of O-alkylglycerophospho-l-serine analogs" @default.
- W2043663359 cites W1498074507 @default.
- W2043663359 cites W1568769949 @default.
- W2043663359 cites W1897509355 @default.
- W2043663359 cites W1965379624 @default.
- W2043663359 cites W1978696094 @default.
- W2043663359 cites W1980364995 @default.
- W2043663359 cites W1983600681 @default.
- W2043663359 cites W1998490733 @default.
- W2043663359 cites W2003007702 @default.
- W2043663359 cites W2027907081 @default.
- W2043663359 cites W2053942504 @default.
- W2043663359 cites W2057557337 @default.
- W2043663359 cites W2060355913 @default.
- W2043663359 cites W2065663979 @default.
- W2043663359 cites W2073384149 @default.
- W2043663359 cites W2076861993 @default.
- W2043663359 cites W2077316333 @default.
- W2043663359 cites W2079260075 @default.
- W2043663359 cites W2472735355 @default.
- W2043663359 cites W4250038822 @default.
- W2043663359 cites W2061154236 @default.
- W2043663359 doi "https://doi.org/10.1016/0009-3084(90)90064-x" @default.
- W2043663359 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2114225" @default.
- W2043663359 hasPublicationYear "1990" @default.
- W2043663359 type Work @default.
- W2043663359 sameAs 2043663359 @default.
- W2043663359 citedByCount "20" @default.
- W2043663359 countsByYear W20436633592023 @default.
- W2043663359 crossrefType "journal-article" @default.
- W2043663359 hasAuthorship W2043663359A5018224101 @default.
- W2043663359 hasAuthorship W2043663359A5059409314 @default.
- W2043663359 hasAuthorship W2043663359A5074023473 @default.
- W2043663359 hasAuthorship W2043663359A5075251959 @default.
- W2043663359 hasAuthorship W2043663359A5083765016 @default.
- W2043663359 hasAuthorship W2043663359A5089898334 @default.
- W2043663359 hasConcept C11960822 @default.
- W2043663359 hasConcept C162356407 @default.
- W2043663359 hasConcept C185592680 @default.
- W2043663359 hasConcept C199033913 @default.
- W2043663359 hasConcept C202751555 @default.
- W2043663359 hasConcept C2776414213 @default.
- W2043663359 hasConcept C3019479964 @default.
- W2043663359 hasConcept C3020616263 @default.
- W2043663359 hasConcept C43617362 @default.
- W2043663359 hasConcept C502942594 @default.
- W2043663359 hasConcept C55493867 @default.
- W2043663359 hasConcept C71240020 @default.
- W2043663359 hasConcept C86803240 @default.
- W2043663359 hasConceptScore W2043663359C11960822 @default.
- W2043663359 hasConceptScore W2043663359C162356407 @default.
- W2043663359 hasConceptScore W2043663359C185592680 @default.
- W2043663359 hasConceptScore W2043663359C199033913 @default.
- W2043663359 hasConceptScore W2043663359C202751555 @default.
- W2043663359 hasConceptScore W2043663359C2776414213 @default.
- W2043663359 hasConceptScore W2043663359C3019479964 @default.
- W2043663359 hasConceptScore W2043663359C3020616263 @default.
- W2043663359 hasConceptScore W2043663359C43617362 @default.
- W2043663359 hasConceptScore W2043663359C502942594 @default.
- W2043663359 hasConceptScore W2043663359C55493867 @default.
- W2043663359 hasConceptScore W2043663359C71240020 @default.
- W2043663359 hasConceptScore W2043663359C86803240 @default.
- W2043663359 hasIssue "2" @default.
- W2043663359 hasLocation W20436633591 @default.
- W2043663359 hasLocation W20436633592 @default.
- W2043663359 hasOpenAccess W2043663359 @default.
- W2043663359 hasPrimaryLocation W20436633591 @default.
- W2043663359 hasRelatedWork W1973671612 @default.
- W2043663359 hasRelatedWork W1973978636 @default.
- W2043663359 hasRelatedWork W1994875678 @default.
- W2043663359 hasRelatedWork W2016245700 @default.
- W2043663359 hasRelatedWork W2017146682 @default.
- W2043663359 hasRelatedWork W2039617123 @default.
- W2043663359 hasRelatedWork W2070414949 @default.
- W2043663359 hasRelatedWork W2088612255 @default.
- W2043663359 hasRelatedWork W2158367185 @default.
- W2043663359 hasRelatedWork W2415961012 @default.
- W2043663359 hasVolume "54" @default.
- W2043663359 isParatext "false" @default.
- W2043663359 isRetracted "false" @default.
- W2043663359 magId "2043663359" @default.
- W2043663359 workType "article" @default.