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• W2043685761 abstract "1 The pharmacology of analgesic drugs with mixed agonist-antagonist action is reviewed in the light of the theory of drug action at single and multiple receptors. 2 Evidence for a heterogeneous population of opiate receptors in mammalian brain and in isolated tissue preparations is discussed. 3 The unusual pharmacological and pharmacokinetic profiles of the oripavine derivative buprenorphine are discussed in relation to the action of the drug at a molecular level." @default.
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• W2043685761 date "1979-06-01" @default.
• W2043685761 modified "2023-10-16" @default.
• W2043685761 title "Animal and molecular pharmacology of mixed agonist-antagonist analgesic drugs." @default.
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• W2043685761 doi "https://doi.org/10.1111/j.1365-2125.1979.tb04701.x" @default.
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