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- W2043699984 abstract "Different brain components can evolve in a coordinated manner or they can show divergent evolutionary trajectories according to a mosaic pattern of variation. Understanding the relationship between these brain evolutionary patterns, which are not mutually exclusive, can be informed by the examination of intraspecific variation. Our study evaluates patterns of brain anatomical covariation in chimpanzees and humans to infer their influence on brain evolution in the hominin clade. We show that chimpanzee and human brains have a modular structure that may have facilitated mosaic evolution from their last common ancestor. Spatially adjacent regions covary with one another to the strongest degree and separated regions are more independent from each other, which might be related to a predominance of local association connectivity. Despite the undoubted importance of developmental and functional factors in determining brain morphology, we find that these constraints are subordinate to the primary effect of local spatial interactions." @default.
- W2043699984 created "2016-06-24" @default.
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- W2043699984 date "2014-07-22" @default.
- W2043699984 modified "2023-10-12" @default.
- W2043699984 title "Modular structure facilitates mosaic evolution of the brain in chimpanzees and humans" @default.
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- W2043699984 doi "https://doi.org/10.1038/ncomms5469" @default.
- W2043699984 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4144426" @default.
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