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- W2043717583 abstract "PURPOSE: Midazolam is a rapidly acting benzodiazepine commonly used for conscious sedation during medical procedures, such as fiberoptic bronchoscopy. Midazolam is metabolized in the liver by cytochrome P4503A (CYP3A) enzymes. Recent guidelines suggest that midazolam should not be used concomitantly with Protease Inhibitors (PI) because PI's inhibit CYP3A enzymes, theoretically increasing sedation and the potential for serious adverse effects. The purpose of the present study is to investigate whether there is evidence of prolonged sedation and increased adverse effects among individuals taking PI's who receive intravenous midazolam during bronchoscopy." @default.
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- W2043717583 date "2007-10-01" @default.
- W2043717583 modified "2023-10-18" @default.
- W2043717583 title "EVALUATING THE SAFETY OF MIDAZOLAM FOR PROCEDURAL SEDATION IN HUMAN IMMUNODEFICIENCY VIRUS-SEROPOSITIVE PATIENTS ON PROTEASE INHIBITORS" @default.
- W2043717583 doi "https://doi.org/10.1378/chest.132.4_meetingabstracts.438" @default.
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