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- W2043736690 abstract "This article reviews the evolution of the development of vaccines against the major fungal pathogens, the state of art of these attempts and future prospects for vaccines for human and veterinary use. The article includes descriptions of the pathogens discussed, the mycoses they cause, their antigenicity, the immune response that they induce in the host and the underlying mechanisms. The final chapters address attempts to develop vaccines in experimental animal models and report on human trials for a selected number of fungi.L'article passe en revue l'évolution du développement des vaccins contre les principaux champignons pathogènes et fait le point de l'état actuel de leurs essais et de leurs perspectives d'avenir en médecine humaine et vétérinaire. Il inclue la description des champignons pathogènes impliqués, des mycoses dont ils sont responsables, de leur antigénicité et de la réponse immunitaire qu'ils induisent chez leur hôte et des mécanismes sous-jacents. Le dernier chapitre rapporte les tentatives pour développer des vaccins sur des modèles animaux expérimentaux et rend compte des essais cliniques pour quelques champignons pathogènes." @default.
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- W2043736690 date "1998-05-01" @default.
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- W2043736690 title "Immune responses to naturally acquired Pneumocystis carinii in gene disruption mutant mice" @default.
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- W2043736690 doi "https://doi.org/10.1016/s0923-2494(98)80766-9" @default.
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