FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043812712> ?p ?o ?g. }

• W2043812712 endingPage "1206" @default.
• W2043812712 startingPage "1202" @default.
• W2043812712 abstract "To determine whether polymorphism of apolipoprotein E--notably, the e4 allele--predicts cognitive deterioration in the general population.Population based cohort investigated in 1990 and in 1993.Zutphen, the Netherlands.Representative cohort of 538 Dutch men aged 70-89 at baseline.Cognitive function assessed by mini mental state examination, change in cognitive function and incidence of impaired cognitive function at three years.The baseline prevalence of impaired cognitive function (mini mental state examination score < or = 25) was higher among carriers of the e4 allele compared with men without the allele (41.0% (55) v 31.1% (122) P = 0.03), and this result was still valid after adjustment for age, occupation, smoking, alcohol use, and cardiovascular diseases. The decline in cognitive function at three years was largest in men homozygous for e4 (-2.4 points), intermediate in those heterozygous for e4 (-0.7 points), and lowest in men without e4 (-0.1 points), and it was independent of other risk factors (P = 0.02). The risk of developing impaired cognitive function during follow up was significantly increased in allele carriers compared with non-carriers (27.6% (16/58) v 15.5% (32/207)). The adjusted odds ratio was 2.87 (95% confidence interval 1.29 to 6.42). Twenty two per cent of the risk of developing impaired cognitive function in this population may be attributable to the e4 allele.The apolipoprotein e4 allele predisposes to cognitive decline in a general population of elderly men." @default.
• W2043812712 created "2016-06-24" @default.
• W2043812712 creator A5018722034 @default.
• W2043812712 creator A5025131217 @default.
• W2043812712 creator A5053215549 @default.
• W2043812712 creator A5058855272 @default.
• W2043812712 creator A5076336171 @default.
• W2043812712 creator A5083018553 @default.
• W2043812712 date "1994-11-05" @default.
• W2043812712 modified "2023-09-24" @default.
• W2043812712 title "Apolipoprotein e4 allele and cognitive decline in elderly men" @default.
• W2043812712 cites W1534056652 @default.
• W2043812712 cites W1590095886 @default.
• W2043812712 cites W1602655991 @default.
• W2043812712 cites W1847168837 @default.
• W2043812712 cites W1966433708 @default.
• W2043812712 cites W1971718473 @default.
• W2043812712 cites W2008854521 @default.
• W2043812712 cites W2011199056 @default.
• W2043812712 cites W2021181758 @default.
• W2043812712 cites W2036362108 @default.
• W2043812712 cites W2058161128 @default.
• W2043812712 cites W2061142443 @default.
• W2043812712 cites W2066644955 @default.
• W2043812712 cites W2069863984 @default.
• W2043812712 cites W2072682191 @default.
• W2043812712 cites W2077219082 @default.
• W2043812712 cites W2091924214 @default.
• W2043812712 cites W2096499083 @default.
• W2043812712 cites W2097608504 @default.
• W2043812712 cites W2109140840 @default.
• W2043812712 cites W2148080316 @default.
• W2043812712 cites W2153716000 @default.
• W2043812712 cites W2167311298 @default.
• W2043812712 cites W2259875908 @default.
• W2043812712 cites W2290417510 @default.
• W2043812712 cites W4233622592 @default.
• W2043812712 cites W2621518294 @default.
• W2043812712 doi "https://doi.org/10.1136/bmj.309.6963.1202" @default.
• W2043812712 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2541698" @default.
• W2043812712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7987151" @default.
• W2043812712 hasPublicationYear "1994" @default.
• W2043812712 type Work @default.
• W2043812712 sameAs 2043812712 @default.
• W2043812712 citedByCount "152" @default.
• W2043812712 countsByYear W20438127122012 @default.
• W2043812712 countsByYear W20438127122014 @default.
• W2043812712 countsByYear W20438127122015 @default.
• W2043812712 countsByYear W20438127122016 @default.
• W2043812712 countsByYear W20438127122017 @default.
• W2043812712 countsByYear W20438127122019 @default.
• W2043812712 countsByYear W20438127122020 @default.
• W2043812712 countsByYear W20438127122021 @default.
• W2043812712 countsByYear W20438127122022 @default.
• W2043812712 crossrefType "journal-article" @default.
• W2043812712 hasAuthorship W2043812712A5018722034 @default.
• W2043812712 hasAuthorship W2043812712A5025131217 @default.
• W2043812712 hasAuthorship W2043812712A5053215549 @default.
• W2043812712 hasAuthorship W2043812712A5058855272 @default.
• W2043812712 hasAuthorship W2043812712A5076336171 @default.
• W2043812712 hasAuthorship W2043812712A5083018553 @default.
• W2043812712 hasBestOaLocation W20438127122 @default.
• W2043812712 hasConcept C104317684 @default.
• W2043812712 hasConcept C118552586 @default.
• W2043812712 hasConcept C126322002 @default.
• W2043812712 hasConcept C144024400 @default.
• W2043812712 hasConcept C149923435 @default.
• W2043812712 hasConcept C156957248 @default.
• W2043812712 hasConcept C15744967 @default.
• W2043812712 hasConcept C169900460 @default.
• W2043812712 hasConcept C180754005 @default.
• W2043812712 hasConcept C2779134260 @default.
• W2043812712 hasConcept C2779483572 @default.
• W2043812712 hasConcept C2908647359 @default.
• W2043812712 hasConcept C2984863031 @default.
• W2043812712 hasConcept C44249647 @default.
• W2043812712 hasConcept C54355233 @default.
• W2043812712 hasConcept C57089818 @default.
• W2043812712 hasConcept C71924100 @default.
• W2043812712 hasConcept C72563966 @default.
• W2043812712 hasConcept C74909509 @default.
• W2043812712 hasConcept C86803240 @default.
• W2043812712 hasConcept C99454951 @default.
• W2043812712 hasConceptScore W2043812712C104317684 @default.
• W2043812712 hasConceptScore W2043812712C118552586 @default.
• W2043812712 hasConceptScore W2043812712C126322002 @default.
• W2043812712 hasConceptScore W2043812712C144024400 @default.
• W2043812712 hasConceptScore W2043812712C149923435 @default.
• W2043812712 hasConceptScore W2043812712C156957248 @default.
• W2043812712 hasConceptScore W2043812712C15744967 @default.
• W2043812712 hasConceptScore W2043812712C169900460 @default.
• W2043812712 hasConceptScore W2043812712C180754005 @default.
• W2043812712 hasConceptScore W2043812712C2779134260 @default.
• W2043812712 hasConceptScore W2043812712C2779483572 @default.
• W2043812712 hasConceptScore W2043812712C2908647359 @default.
• W2043812712 hasConceptScore W2043812712C2984863031 @default.
• W2043812712 hasConceptScore W2043812712C44249647 @default.
• W2043812712 hasConceptScore W2043812712C54355233 @default.

• next