FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043819578> ?p ?o ?g. }

• W2043819578 endingPage "e19433" @default.
• W2043819578 startingPage "e19433" @default.
• W2043819578 abstract "Milk is the single source of nutrients for the newborn mammal. The composition of milk of different mammals has been adapted during evolution of the species to fulfill the needs of the offspring. Milk not only provides nutrients, but it also serves as a medium for transfer of host defense components to the offspring. The host defense proteins in the milk of different mammalian species are expected to reveal signatures of evolution. The aim of this study is therefore to study the difference in the host defense proteome of human and bovine milk. We analyzed human and bovine milk using a shot-gun proteomics approach focusing on host defense-related proteins. In total, 268 proteins in human milk and 269 proteins in bovine milk were identified. Of these, 44 from human milk and 51 from bovine milk are related to the host defense system. Of these proteins, 33 were found in both species but with significantly different quantities. High concentrations of proteins involved in the mucosal immune system, immunoglobulin A, CD14, lactoferrin, and lysozyme, were present in human milk. The human newborn is known to be deficient for at least two of these proteins (immunoglobulin A and CD14). On the other hand, antimicrobial proteins (5 cathelicidins and lactoperoxidase) were abundant in bovine milk. The high concentration of lactoperoxidase is probably linked to the high amount of thiocyanate in the plant-based diet of cows. This first detailed analysis of host defense proteins in human and bovine milk is an important step in understanding the function of milk in the development of the immune system of these two mammals." @default.
• W2043819578 created "2016-06-24" @default.
• W2043819578 creator A5004181703 @default.
• W2043819578 creator A5005546551 @default.
• W2043819578 creator A5009181716 @default.
• W2043819578 creator A5020911322 @default.
• W2043819578 creator A5034326340 @default.
• W2043819578 creator A5060544376 @default.
• W2043819578 creator A5069460407 @default.
• W2043819578 date "2011-04-27" @default.
• W2043819578 modified "2023-09-29" @default.
• W2043819578 title "The Host Defense Proteome of Human and Bovine Milk" @default.
• W2043819578 cites W1586360340 @default.
• W2043819578 cites W1625124020 @default.
• W2043819578 cites W1964673197 @default.
• W2043819578 cites W1965169001 @default.
• W2043819578 cites W1981424925 @default.
• W2043819578 cites W1986887325 @default.
• W2043819578 cites W1991765113 @default.
• W2043819578 cites W1995958771 @default.
• W2043819578 cites W2001567020 @default.
• W2043819578 cites W2020668335 @default.
• W2043819578 cites W2029903925 @default.
• W2043819578 cites W2036732296 @default.
• W2043819578 cites W2037199116 @default.
• W2043819578 cites W2039595635 @default.
• W2043819578 cites W2040543150 @default.
• W2043819578 cites W2040835861 @default.
• W2043819578 cites W2044110769 @default.
• W2043819578 cites W2045340947 @default.
• W2043819578 cites W2049925143 @default.
• W2043819578 cites W2049998833 @default.
• W2043819578 cites W2050068722 @default.
• W2043819578 cites W2051142131 @default.
• W2043819578 cites W2060719865 @default.
• W2043819578 cites W2065683366 @default.
• W2043819578 cites W2080752012 @default.
• W2043819578 cites W2090209417 @default.
• W2043819578 cites W2115495886 @default.
• W2043819578 cites W2116991361 @default.
• W2043819578 cites W2127561345 @default.
• W2043819578 cites W2140921118 @default.
• W2043819578 cites W2145627213 @default.
• W2043819578 cites W2153132589 @default.
• W2043819578 cites W2153493935 @default.
• W2043819578 cites W2158477560 @default.
• W2043819578 cites W1965155004 @default.
• W2043819578 doi "https://doi.org/10.1371/journal.pone.0019433" @default.
• W2043819578 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3083434" @default.
• W2043819578 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21556375" @default.
• W2043819578 hasPublicationYear "2011" @default.
• W2043819578 type Work @default.
• W2043819578 sameAs 2043819578 @default.
• W2043819578 citedByCount "195" @default.
• W2043819578 countsByYear W20438195782012 @default.
• W2043819578 countsByYear W20438195782013 @default.
• W2043819578 countsByYear W20438195782014 @default.
• W2043819578 countsByYear W20438195782015 @default.
• W2043819578 countsByYear W20438195782016 @default.
• W2043819578 countsByYear W20438195782017 @default.
• W2043819578 countsByYear W20438195782018 @default.
• W2043819578 countsByYear W20438195782019 @default.
• W2043819578 countsByYear W20438195782020 @default.
• W2043819578 countsByYear W20438195782021 @default.
• W2043819578 countsByYear W20438195782022 @default.
• W2043819578 countsByYear W20438195782023 @default.
• W2043819578 crossrefType "journal-article" @default.
• W2043819578 hasAuthorship W2043819578A5004181703 @default.
• W2043819578 hasAuthorship W2043819578A5005546551 @default.
• W2043819578 hasAuthorship W2043819578A5009181716 @default.
• W2043819578 hasAuthorship W2043819578A5020911322 @default.
• W2043819578 hasAuthorship W2043819578A5034326340 @default.
• W2043819578 hasAuthorship W2043819578A5060544376 @default.
• W2043819578 hasAuthorship W2043819578A5069460407 @default.
• W2043819578 hasBestOaLocation W20438195781 @default.
• W2043819578 hasConcept C104397665 @default.
• W2043819578 hasConcept C126831891 @default.
• W2043819578 hasConcept C162008176 @default.
• W2043819578 hasConcept C181199279 @default.
• W2043819578 hasConcept C201956729 @default.
• W2043819578 hasConcept C2776966407 @default.
• W2043819578 hasConcept C2779170986 @default.
• W2043819578 hasConcept C2992940123 @default.
• W2043819578 hasConcept C54355233 @default.
• W2043819578 hasConcept C55493867 @default.
• W2043819578 hasConcept C86803240 @default.
• W2043819578 hasConcept C89423630 @default.
• W2043819578 hasConceptScore W2043819578C104397665 @default.
• W2043819578 hasConceptScore W2043819578C126831891 @default.
• W2043819578 hasConceptScore W2043819578C162008176 @default.
• W2043819578 hasConceptScore W2043819578C181199279 @default.
• W2043819578 hasConceptScore W2043819578C201956729 @default.
• W2043819578 hasConceptScore W2043819578C2776966407 @default.
• W2043819578 hasConceptScore W2043819578C2779170986 @default.
• W2043819578 hasConceptScore W2043819578C2992940123 @default.
• W2043819578 hasConceptScore W2043819578C54355233 @default.
• W2043819578 hasConceptScore W2043819578C55493867 @default.
• W2043819578 hasConceptScore W2043819578C86803240 @default.

• next