FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043886136> ?p ?o ?g. }

• W2043886136 endingPage "362" @default.
• W2043886136 startingPage "357" @default.
• W2043886136 abstract "Glioma is the most common type of primary brain malignancy in adults. The X-ray repair cross-complementing group 1 (XRCC1) is an important candidate gene for influencing the pathogenesis of glioma. This study aimed to evaluate the potential association between XRCC1 genetic polymorphisms and glioma susceptibility. This case–control study was conducted in Chinese Han populations consisting of 620 glioma cases and 630 cancer-free controls. XRCC1 genetic polymorphisms were detected by the polymerase chain reaction–restriction fragment length polymorphism and verified using DNA sequencing methods. The c.910A>G and c.1779C>G genetic polymorphisms were identified in this study. Our data suggested that the genotypes/alleles of these two genetic polymorphisms were statistically associated with the increased risk of glioma. As for c.910A>G, the risk of glioma for genotype GG was significantly higher than wild genotype AA (odds ratio (OR) = 1.98, 95 % confidence interval (CI) 1.33–2.94, P = 0.001). As for c.1779C>G, the genotype GG was statistically associated with the increased risk of glioma compared to wild genotype CC (OR = 1.80, 95 % CI 1.17–2.78, P = 0.007). Both of alleles G in c.910A>G and c.1779C>G may contribute to glioma susceptibility (G versus (vs.) A, OR = 1.30, 95 % CI 1.09–1.54, P = 0.003; G vs. C, OR = 1.19, 95 % CI 1.00–1.42, P = 0.045). Our findings indicate that the c.910A>G and c.1779C>G genetic polymorphisms are associated with the susceptibility to glioma in Chinese Han populations and might be used as molecular markers for evaluating glioma risk." @default.
• W2043886136 created "2016-06-24" @default.
• W2043886136 creator A5035664858 @default.
• W2043886136 creator A5045877748 @default.
• W2043886136 creator A5051624228 @default.
• W2043886136 creator A5072243575 @default.
• W2043886136 date "2013-08-06" @default.
• W2043886136 modified "2023-10-18" @default.
• W2043886136 title "Genetic polymorphisms in XRCC1 gene and susceptibility to glioma in Chinese Han population" @default.
• W2043886136 cites W1975145355 @default.
• W2043886136 cites W1980641700 @default.
• W2043886136 cites W1995747445 @default.
• W2043886136 cites W1997119877 @default.
• W2043886136 cites W2027380102 @default.
• W2043886136 cites W2032399864 @default.
• W2043886136 cites W2034677735 @default.
• W2043886136 cites W2036044314 @default.
• W2043886136 cites W2039810654 @default.
• W2043886136 cites W2042455296 @default.
• W2043886136 cites W2044197183 @default.
• W2043886136 cites W2055475004 @default.
• W2043886136 cites W2057075242 @default.
• W2043886136 cites W2058442351 @default.
• W2043886136 cites W2067253938 @default.
• W2043886136 cites W2084786231 @default.
• W2043886136 cites W2091060185 @default.
• W2043886136 cites W2098341282 @default.
• W2043886136 cites W2101959907 @default.
• W2043886136 cites W2106502408 @default.
• W2043886136 cites W2130188373 @default.
• W2043886136 cites W2144669949 @default.
• W2043886136 cites W2159963856 @default.
• W2043886136 doi "https://doi.org/10.1007/s13277-013-1050-2" @default.
• W2043886136 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23918303" @default.
• W2043886136 hasPublicationYear "2013" @default.
• W2043886136 type Work @default.
• W2043886136 sameAs 2043886136 @default.
• W2043886136 citedByCount "3" @default.
• W2043886136 countsByYear W20438861362014 @default.
• W2043886136 countsByYear W20438861362015 @default.
• W2043886136 crossrefType "journal-article" @default.
• W2043886136 hasAuthorship W2043886136A5035664858 @default.
• W2043886136 hasAuthorship W2043886136A5045877748 @default.
• W2043886136 hasAuthorship W2043886136A5051624228 @default.
• W2043886136 hasAuthorship W2043886136A5072243575 @default.
• W2043886136 hasConcept C104317684 @default.
• W2043886136 hasConcept C126322002 @default.
• W2043886136 hasConcept C135763542 @default.
• W2043886136 hasConcept C153209595 @default.
• W2043886136 hasConcept C156957248 @default.
• W2043886136 hasConcept C180754005 @default.
• W2043886136 hasConcept C2776999993 @default.
• W2043886136 hasConcept C2778227246 @default.
• W2043886136 hasConcept C54355233 @default.
• W2043886136 hasConcept C67636389 @default.
• W2043886136 hasConcept C71924100 @default.
• W2043886136 hasConcept C86803240 @default.
• W2043886136 hasConceptScore W2043886136C104317684 @default.
• W2043886136 hasConceptScore W2043886136C126322002 @default.
• W2043886136 hasConceptScore W2043886136C135763542 @default.
• W2043886136 hasConceptScore W2043886136C153209595 @default.
• W2043886136 hasConceptScore W2043886136C156957248 @default.
• W2043886136 hasConceptScore W2043886136C180754005 @default.
• W2043886136 hasConceptScore W2043886136C2776999993 @default.
• W2043886136 hasConceptScore W2043886136C2778227246 @default.
• W2043886136 hasConceptScore W2043886136C54355233 @default.
• W2043886136 hasConceptScore W2043886136C67636389 @default.
• W2043886136 hasConceptScore W2043886136C71924100 @default.
• W2043886136 hasConceptScore W2043886136C86803240 @default.
• W2043886136 hasIssue "1" @default.
• W2043886136 hasLocation W20438861361 @default.
• W2043886136 hasLocation W20438861362 @default.
• W2043886136 hasOpenAccess W2043886136 @default.
• W2043886136 hasPrimaryLocation W20438861361 @default.
• W2043886136 hasRelatedWork W1492270877 @default.
• W2043886136 hasRelatedWork W1769313417 @default.
• W2043886136 hasRelatedWork W2036454960 @default.
• W2043886136 hasRelatedWork W2043886136 @default.
• W2043886136 hasRelatedWork W2056955492 @default.
• W2043886136 hasRelatedWork W2084786231 @default.
• W2043886136 hasRelatedWork W2103125327 @default.
• W2043886136 hasRelatedWork W2106502408 @default.
• W2043886136 hasRelatedWork W2168809780 @default.
• W2043886136 hasRelatedWork W3206047998 @default.
• W2043886136 hasVolume "35" @default.
• W2043886136 isParatext "false" @default.
• W2043886136 isRetracted "false" @default.
• W2043886136 magId "2043886136" @default.
• W2043886136 workType "article" @default.