FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043896263> ?p ?o ?g. }

• W2043896263 endingPage "6560" @default.
• W2043896263 startingPage "6548" @default.
• W2043896263 abstract "The aim of our study was to estimate the surface expressions of CD95 (APO-1/Fas) antigen and the intracellular expressions of anti-apoptotic protein Bcl-2 and pro-apoptotic protein Bax in CD4(+)CD25(+)FoxP3(+) T regulatory lymphocytes (Tregs) as well as the percentage of CD8(+)CD28(+) T cytotoxic cells in peripheral blood of patients with pre-eclampsia in comparison with healthy pregnant women in the third trimester of physiological pregnancy. Twenty-four women with pre-eclampsia and 20 normal third trimester pregnant women were included in the study. The lymphocytes were isolated from peripheral blood samples and labeled with monoclonal antibodies. The expressions of surface antigens and intracellular proteins were estimated using flow cytometry. The population of CD4(+)CD25(+)FoxP3(+) Treg cells was significantly lower in peripheral blood of patients with pre-eclampsia when compared to normal third trimester pregnant women. The percentages of CD4(+)CD25(+)FoxP3(+) Treg cells that express Bcl-2 protein were significantly lower in peripheral blood of patients with pre-eclampsia when compared to healthy pregnant women, whereas the percentages of CD4(+)CD25(+)FoxP3(+) Treg cells with the expressions of Bax protein did not differ in both groups. Moreover, the mean fluorescence intensity (MFI) of Bcl-2 protein in CD4(+)CD25(+)FoxP3(+) Treg cells was significantly lower and MFI of Bax protein significantly higher in pre-eclampsia when compared to the control group. The percentage of CD8(+)CD28(+) T cells did not differ in both studied groups but MFI of CD28 antigen on T CD8(+) cells was significantly higher in pre-eclampsia when compared to the control group. The obtained results suggest that the deficit of CD4(+)CD25(+)FoxP3(+) Treg lymphocytes which is observed in pre-eclampsia may be associated with altered apoptosis signaling in Tregs." @default.
• W2043896263 created "2016-06-24" @default.
• W2043896263 creator A5003297637 @default.
• W2043896263 creator A5031619166 @default.
• W2043896263 creator A5042881462 @default.
• W2043896263 creator A5046196284 @default.
• W2043896263 creator A5066945441 @default.
• W2043896263 creator A5085032356 @default.
• W2043896263 creator A5085299270 @default.
• W2043896263 date "2012-05-29" @default.
• W2043896263 modified "2023-10-14" @default.
• W2043896263 title "Apoptosis Signaling Is Altered in CD4+CD25+FoxP3+ T Regulatory Lymphocytes in Pre-Eclampsia" @default.
• W2043896263 cites W1560277370 @default.
• W2043896263 cites W1695756438 @default.
• W2043896263 cites W1741227320 @default.
• W2043896263 cites W1965712768 @default.
• W2043896263 cites W1983895762 @default.
• W2043896263 cites W1987844503 @default.
• W2043896263 cites W1989496524 @default.
• W2043896263 cites W1995331340 @default.
• W2043896263 cites W1999764514 @default.
• W2043896263 cites W2001740313 @default.
• W2043896263 cites W2002726823 @default.
• W2043896263 cites W2007466030 @default.
• W2043896263 cites W2012680181 @default.
• W2043896263 cites W2018020394 @default.
• W2043896263 cites W2020261787 @default.
• W2043896263 cites W2022196368 @default.
• W2043896263 cites W2023994866 @default.
• W2043896263 cites W2024178516 @default.
• W2043896263 cites W2029208213 @default.
• W2043896263 cites W2036822121 @default.
• W2043896263 cites W2041466047 @default.
• W2043896263 cites W2058232542 @default.
• W2043896263 cites W2062765335 @default.
• W2043896263 cites W2076819781 @default.
• W2043896263 cites W2083962256 @default.
• W2043896263 cites W2097811455 @default.
• W2043896263 cites W2104732966 @default.
• W2043896263 cites W2110252464 @default.
• W2043896263 cites W2112820346 @default.
• W2043896263 cites W2117348443 @default.
• W2043896263 cites W2121501744 @default.
• W2043896263 cites W2131958114 @default.
• W2043896263 cites W2134979684 @default.
• W2043896263 cites W2139226941 @default.
• W2043896263 cites W2139802799 @default.
• W2043896263 cites W2150356881 @default.
• W2043896263 cites W2153095488 @default.
• W2043896263 cites W2158121126 @default.
• W2043896263 cites W2580064549 @default.
• W2043896263 cites W2737785069 @default.
• W2043896263 cites W45439142 @default.
• W2043896263 doi "https://doi.org/10.3390/ijms13066548" @default.
• W2043896263 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3397481" @default.
• W2043896263 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22837649" @default.
• W2043896263 hasPublicationYear "2012" @default.
• W2043896263 type Work @default.
• W2043896263 sameAs 2043896263 @default.
• W2043896263 citedByCount "25" @default.
• W2043896263 countsByYear W20438962632013 @default.
• W2043896263 countsByYear W20438962632014 @default.
• W2043896263 countsByYear W20438962632015 @default.
• W2043896263 countsByYear W20438962632016 @default.
• W2043896263 countsByYear W20438962632017 @default.
• W2043896263 countsByYear W20438962632018 @default.
• W2043896263 countsByYear W20438962632019 @default.
• W2043896263 countsByYear W20438962632020 @default.
• W2043896263 countsByYear W20438962632021 @default.
• W2043896263 countsByYear W20438962632022 @default.
• W2043896263 countsByYear W20438962632023 @default.
• W2043896263 crossrefType "journal-article" @default.
• W2043896263 hasAuthorship W2043896263A5003297637 @default.
• W2043896263 hasAuthorship W2043896263A5031619166 @default.
• W2043896263 hasAuthorship W2043896263A5042881462 @default.
• W2043896263 hasAuthorship W2043896263A5046196284 @default.
• W2043896263 hasAuthorship W2043896263A5066945441 @default.
• W2043896263 hasAuthorship W2043896263A5085032356 @default.
• W2043896263 hasAuthorship W2043896263A5085299270 @default.
• W2043896263 hasBestOaLocation W20438962631 @default.
• W2043896263 hasConcept C126322002 @default.
• W2043896263 hasConcept C134018914 @default.
• W2043896263 hasConcept C147483822 @default.
• W2043896263 hasConcept C148125776 @default.
• W2043896263 hasConcept C154317977 @default.
• W2043896263 hasConcept C16685009 @default.
• W2043896263 hasConcept C167672396 @default.
• W2043896263 hasConcept C190283241 @default.
• W2043896263 hasConcept C202751555 @default.
• W2043896263 hasConcept C203014093 @default.
• W2043896263 hasConcept C2776090121 @default.
• W2043896263 hasConcept C2779727006 @default.
• W2043896263 hasConcept C2908647359 @default.
• W2043896263 hasConcept C55493867 @default.
• W2043896263 hasConcept C71924100 @default.
• W2043896263 hasConcept C79484868 @default.
• W2043896263 hasConcept C86803240 @default.
• W2043896263 hasConcept C8891405 @default.

• next