FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043905324> ?p ?o ?g. }

• W2043905324 endingPage "693" @default.
• W2043905324 startingPage "685" @default.
• W2043905324 abstract "Abstract We have used primary cultures of rat striatum to study the effects of ATP analogues on the elongation of astrocytic processes, a parameter of astroglial cell differentiation. Parallel studies were performed with basic fibroblast growth factor, a known regulator of astroglial cell function. After three days in culture, both the growth factor and αβ‐methylene‐ATP induced dramatic increases in the mean length of astrocytic processes/cell. For both agents, effects were dose‐dependent. The effect of αβ‐methylene‐ATP was antagonized by the trypanoside suramin and mimicked by 2‐methyl‐thio‐ATP, suggesting the involvement of a suramin‐sensitive P2‐purinoceptor. Neither an additive nor a synergistic effect between αβ‐methylene‐ATP and basic fibroblast growth factor on the elongation of processes was detected in cultures exposed to both agents. Indeed, an inhibition with respect to the effects induced by either agent alone was recorded, suggesting that the growth factor and the purine analogue can modulate astrocytic differentiation by activation of common intracellular pathways. It is concluded that, like basic fibroblast growth factor, ATP can promote the maturation of astrocytes towards a more differentiated phenotype characterized by the presence of longer astrocytic processes. These findings might have interesting implications for astroglial cell differentiation during brain development and for ischemia‐ and trauma‐associated hypergliosis." @default.
• W2043905324 created "2016-06-24" @default.
• W2043905324 creator A5048473197 @default.
• W2043905324 creator A5051019086 @default.
• W2043905324 creator A5058369958 @default.
• W2043905324 creator A5062628094 @default.
• W2043905324 creator A5078216624 @default.
• W2043905324 creator A5085082688 @default.
• W2043905324 date "1995-11-01" @default.
• W2043905324 modified "2023-10-18" @default.
• W2043905324 title "Effects of ATP analogues and basic fibroblast growth factor on astroglial cell differentiation in primary cultures of rat striatum" @default.
• W2043905324 cites W1571749791 @default.
• W2043905324 cites W1968143827 @default.
• W2043905324 cites W1979152924 @default.
• W2043905324 cites W1984454036 @default.
• W2043905324 cites W1986571729 @default.
• W2043905324 cites W1992559673 @default.
• W2043905324 cites W1999320859 @default.
• W2043905324 cites W2003437645 @default.
• W2043905324 cites W2003819256 @default.
• W2043905324 cites W2006289803 @default.
• W2043905324 cites W2018481422 @default.
• W2043905324 cites W2030027127 @default.
• W2043905324 cites W2052530663 @default.
• W2043905324 cites W2077974144 @default.
• W2043905324 cites W2081592513 @default.
• W2043905324 cites W2098950208 @default.
• W2043905324 cites W2154021054 @default.
• W2043905324 cites W2172267555 @default.
• W2043905324 cites W981008291 @default.
• W2043905324 doi "https://doi.org/10.1016/0736-5748(95)00064-x" @default.
• W2043905324 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8787859" @default.
• W2043905324 hasPublicationYear "1995" @default.
• W2043905324 type Work @default.
• W2043905324 sameAs 2043905324 @default.
• W2043905324 citedByCount "56" @default.
• W2043905324 countsByYear W20439053242012 @default.
• W2043905324 countsByYear W20439053242014 @default.
• W2043905324 countsByYear W20439053242016 @default.
• W2043905324 countsByYear W20439053242018 @default.
• W2043905324 countsByYear W20439053242021 @default.
• W2043905324 crossrefType "journal-article" @default.
• W2043905324 hasAuthorship W2043905324A5048473197 @default.
• W2043905324 hasAuthorship W2043905324A5051019086 @default.
• W2043905324 hasAuthorship W2043905324A5058369958 @default.
• W2043905324 hasAuthorship W2043905324A5062628094 @default.
• W2043905324 hasAuthorship W2043905324A5078216624 @default.
• W2043905324 hasAuthorship W2043905324A5085082688 @default.
• W2043905324 hasConcept C104317684 @default.
• W2043905324 hasConcept C134018914 @default.
• W2043905324 hasConcept C148738053 @default.
• W2043905324 hasConcept C170493617 @default.
• W2043905324 hasConcept C202751555 @default.
• W2043905324 hasConcept C2775960820 @default.
• W2043905324 hasConcept C2776182878 @default.
• W2043905324 hasConcept C2777542381 @default.
• W2043905324 hasConcept C2777587049 @default.
• W2043905324 hasConcept C2780062018 @default.
• W2043905324 hasConcept C513476851 @default.
• W2043905324 hasConcept C529278444 @default.
• W2043905324 hasConcept C54355233 @default.
• W2043905324 hasConcept C55493867 @default.
• W2043905324 hasConcept C62112901 @default.
• W2043905324 hasConcept C74373430 @default.
• W2043905324 hasConcept C79879829 @default.
• W2043905324 hasConcept C81885089 @default.
• W2043905324 hasConcept C86803240 @default.
• W2043905324 hasConcept C95444343 @default.
• W2043905324 hasConceptScore W2043905324C104317684 @default.
• W2043905324 hasConceptScore W2043905324C134018914 @default.
• W2043905324 hasConceptScore W2043905324C148738053 @default.
• W2043905324 hasConceptScore W2043905324C170493617 @default.
• W2043905324 hasConceptScore W2043905324C202751555 @default.
• W2043905324 hasConceptScore W2043905324C2775960820 @default.
• W2043905324 hasConceptScore W2043905324C2776182878 @default.
• W2043905324 hasConceptScore W2043905324C2777542381 @default.
• W2043905324 hasConceptScore W2043905324C2777587049 @default.
• W2043905324 hasConceptScore W2043905324C2780062018 @default.
• W2043905324 hasConceptScore W2043905324C513476851 @default.
• W2043905324 hasConceptScore W2043905324C529278444 @default.
• W2043905324 hasConceptScore W2043905324C54355233 @default.
• W2043905324 hasConceptScore W2043905324C55493867 @default.
• W2043905324 hasConceptScore W2043905324C62112901 @default.
• W2043905324 hasConceptScore W2043905324C74373430 @default.
• W2043905324 hasConceptScore W2043905324C79879829 @default.
• W2043905324 hasConceptScore W2043905324C81885089 @default.
• W2043905324 hasConceptScore W2043905324C86803240 @default.
• W2043905324 hasConceptScore W2043905324C95444343 @default.
• W2043905324 hasIssue "7" @default.
• W2043905324 hasLocation W20439053241 @default.
• W2043905324 hasLocation W20439053242 @default.
• W2043905324 hasOpenAccess W2043905324 @default.
• W2043905324 hasPrimaryLocation W20439053241 @default.
• W2043905324 hasRelatedWork W1964402123 @default.
• W2043905324 hasRelatedWork W1981954986 @default.
• W2043905324 hasRelatedWork W1992446226 @default.
• W2043905324 hasRelatedWork W2005859037 @default.
• W2043905324 hasRelatedWork W2027090478 @default.

• next