Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043910105> ?p ?o ?g. }
- W2043910105 endingPage "g14" @default.
- W2043910105 startingPage "g14" @default.
- W2043910105 abstract "<b>Objective</b> To examine whether first trimester fetal growth restriction correlates with cardiovascular outcomes in childhood. <b>Design</b> Population based prospective cohort study. <b>Setting</b> City of Rotterdam, the Netherlands. <b>Participants</b> 1184 children with first trimester fetal crown to rump length measurements, whose mothers had a reliable first day of their last menstrual period and a regular menstrual cycle. <b>Main outcomes measures</b> Body mass index, total and abdominal fat distribution, blood pressure, and blood concentrations of cholesterol, triglycerides, insulin, and C peptide at the median age of 6.0 (90% range 5.7-6.8) years. Clustering of cardiovascular risk factors was defined as having three or more of: high android fat mass; high systolic or diastolic blood pressure; low high density lipoprotein cholesterol or high triglycerides concentrations; and high insulin concentrations. <b>Results</b> One standard deviation score greater first trimester fetal crown to rump length was associated with a lower total fat mass (−0.30%, 95% confidence interval −0.57% to −0.03%), android fat mass (−0.07%, −0.12% to −0.02%), android/gynoid fat mass ratio (−0.53, −0.89 to −0.17), diastolic blood pressure (−0.43, −0.84 to −0.01, mm Hg), total cholesterol (−0.05, −0.10 to 0, mmol/L), low density lipoprotein cholesterol (−0.04, −0.09 to 0, mmol/L), and risk of clustering of cardiovascular risk factors (relative risk 0.81, 0.66 to 1.00) in childhood. Additional adjustment for gestational age and weight at birth changed these effect estimates only slightly. Childhood body mass index fully explained the associations of first trimester fetal crown to rump length with childhood total fat mass. First trimester fetal growth was not associated with other cardiovascular outcomes. Longitudinal growth analyses showed that compared with school age children without clustering of cardiovascular risk factors, those with clustering had a smaller first trimester fetal crown to rump length and lower second and third trimester estimated fetal weight but higher weight growth from the age of 6 months onwards. <b>Conclusions</b> Impaired first trimester fetal growth is associated with an adverse cardiovascular risk profile in school age children. Early fetal life might be a critical period for cardiovascular health in later life." @default.
- W2043910105 created "2016-06-24" @default.
- W2043910105 creator A5012921360 @default.
- W2043910105 creator A5028165898 @default.
- W2043910105 creator A5039611937 @default.
- W2043910105 creator A5056326170 @default.
- W2043910105 creator A5073244205 @default.
- W2043910105 creator A5075145005 @default.
- W2043910105 date "2014-01-23" @default.
- W2043910105 modified "2023-10-05" @default.
- W2043910105 title "First trimester fetal growth restriction and cardiovascular risk factors in school age children: population based cohort study" @default.
- W2043910105 cites W1871402548 @default.
- W2043910105 cites W1968532354 @default.
- W2043910105 cites W1974959407 @default.
- W2043910105 cites W1979553170 @default.
- W2043910105 cites W1993785584 @default.
- W2043910105 cites W1995527832 @default.
- W2043910105 cites W2011133918 @default.
- W2043910105 cites W2020985812 @default.
- W2043910105 cites W2031720467 @default.
- W2043910105 cites W2034960978 @default.
- W2043910105 cites W2047367331 @default.
- W2043910105 cites W2049818020 @default.
- W2043910105 cites W2065974896 @default.
- W2043910105 cites W2068978461 @default.
- W2043910105 cites W2072717621 @default.
- W2043910105 cites W2082258863 @default.
- W2043910105 cites W2083854981 @default.
- W2043910105 cites W2096856257 @default.
- W2043910105 cites W2105087430 @default.
- W2043910105 cites W2106234893 @default.
- W2043910105 cites W2106650290 @default.
- W2043910105 cites W2109731037 @default.
- W2043910105 cites W2111954313 @default.
- W2043910105 cites W2114949397 @default.
- W2043910105 cites W2117364688 @default.
- W2043910105 cites W2137635384 @default.
- W2043910105 cites W2142468582 @default.
- W2043910105 cites W2151116622 @default.
- W2043910105 cites W2152628928 @default.
- W2043910105 cites W2158956203 @default.
- W2043910105 cites W2169783774 @default.
- W2043910105 cites W2497721881 @default.
- W2043910105 cites W2726799618 @default.
- W2043910105 cites W2280586107 @default.
- W2043910105 doi "https://doi.org/10.1136/bmj.g14" @default.
- W2043910105 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3901421" @default.
- W2043910105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24458585" @default.
- W2043910105 hasPublicationYear "2014" @default.
- W2043910105 type Work @default.
- W2043910105 sameAs 2043910105 @default.
- W2043910105 citedByCount "240" @default.
- W2043910105 countsByYear W20439101052014 @default.
- W2043910105 countsByYear W20439101052015 @default.
- W2043910105 countsByYear W20439101052016 @default.
- W2043910105 countsByYear W20439101052017 @default.
- W2043910105 countsByYear W20439101052018 @default.
- W2043910105 countsByYear W20439101052019 @default.
- W2043910105 countsByYear W20439101052020 @default.
- W2043910105 countsByYear W20439101052021 @default.
- W2043910105 countsByYear W20439101052022 @default.
- W2043910105 countsByYear W20439101052023 @default.
- W2043910105 crossrefType "journal-article" @default.
- W2043910105 hasAuthorship W2043910105A5012921360 @default.
- W2043910105 hasAuthorship W2043910105A5028165898 @default.
- W2043910105 hasAuthorship W2043910105A5039611937 @default.
- W2043910105 hasAuthorship W2043910105A5056326170 @default.
- W2043910105 hasAuthorship W2043910105A5073244205 @default.
- W2043910105 hasAuthorship W2043910105A5075145005 @default.
- W2043910105 hasBestOaLocation W20439101051 @default.
- W2043910105 hasConcept C126322002 @default.
- W2043910105 hasConcept C131872663 @default.
- W2043910105 hasConcept C134018914 @default.
- W2043910105 hasConcept C188816634 @default.
- W2043910105 hasConcept C2780221984 @default.
- W2043910105 hasConcept C2908647359 @default.
- W2043910105 hasConcept C71924100 @default.
- W2043910105 hasConcept C72563966 @default.
- W2043910105 hasConcept C84393581 @default.
- W2043910105 hasConcept C99454951 @default.
- W2043910105 hasConceptScore W2043910105C126322002 @default.
- W2043910105 hasConceptScore W2043910105C131872663 @default.
- W2043910105 hasConceptScore W2043910105C134018914 @default.
- W2043910105 hasConceptScore W2043910105C188816634 @default.
- W2043910105 hasConceptScore W2043910105C2780221984 @default.
- W2043910105 hasConceptScore W2043910105C2908647359 @default.
- W2043910105 hasConceptScore W2043910105C71924100 @default.
- W2043910105 hasConceptScore W2043910105C72563966 @default.
- W2043910105 hasConceptScore W2043910105C84393581 @default.
- W2043910105 hasConceptScore W2043910105C99454951 @default.
- W2043910105 hasIssue "jan23 1" @default.
- W2043910105 hasLocation W20439101051 @default.
- W2043910105 hasLocation W20439101052 @default.
- W2043910105 hasLocation W20439101053 @default.
- W2043910105 hasLocation W20439101054 @default.
- W2043910105 hasLocation W20439101055 @default.
- W2043910105 hasLocation W20439101056 @default.
- W2043910105 hasLocation W20439101057 @default.