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- W2043916276 abstract "Cellular autoradiography is used to study the transcription patterns of the polytene X chromosomes in Drosophila nasuta nasuta and D. n. albomicans. D. n. nasuta, with 2n = 8, includes a pair of complete heteromorphic sex chromosomes, whereas D. n. albomicans, with 2n = 6, has a pair of metacentric neo-sex chromosomes representing incomplete heteromorphic sex chromosomes. The neo-X chromosome has two euchromatic arms, one representing the ancestral X while the other represents the ancestral autosome 3 chromosomes. The metacentric neo-Y chromosome has one arm with a complete heterochromatic ancestral Y and the other arm with a euchromatic ancestral autosome 3. The transcription study has revealed that the X chromosome in D. n. nasuta is hyperactive, suggesting complete dosage compensation, while in the neo-X chromosome of D. n. albomicans the ancestral X chromosome is hyperactive and the ancestral autosome 3, which is part of the neo-sex chromosome, is similar to any other autosomes. This finding shows dosage compensation on one arm (XLx/-) of the neo-X chromosome, while the other arm (XR3/YR3) is not dosage compensated and has yet to acquire the dosage compensatory mechanism." @default.
- W2043916276 created "2016-06-24" @default.
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- W2043916276 date "2001-01-01" @default.
- W2043916276 modified "2023-09-24" @default.
- W2043916276 title "Autoradiographic study of transcription and dosage compensation in the sex and neo-sex chromosome of <i>Drosophila nasuta nasuta</i> and <i>Drosophila nasuta albomicans</i>" @default.
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- W2043916276 doi "https://doi.org/10.1139/gen-44-1-71" @default.
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