Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043918596> ?p ?o ?g. }
- W2043918596 endingPage "631" @default.
- W2043918596 startingPage "623" @default.
- W2043918596 abstract "The purpose of this study was to investigate the possible antioxidant effect of an aqueous extract of Ajuga iva (Ai) in streptozotocin (STZ)-induced diabetic rats. Twelve diabetic rats were divided into two groups fed a casein diet supplemented or not with Ai (0.5%), for 4 weeks. In vitro, the Ai extract possessed a very high antioxidant effect (1 mg/ml was similar to those of trolox 300 mmol/l). The results indicated that plasma thiobarbituric acid reactive substances (TBARS) values were reduced by 41% in Ai-treated compared with untreated diabetic rats. TBARS concentrations were lower 1.5-fold in liver, 1.8-fold in heart, 1.9-fold in muscle and 2.1-fold in brain in Ai-treated than untreated group. In erythrocytes, Ai treatment increased significantly the activities of glutathione peroxidase (GSH-Px) (+25%) and glutathione reductase (GSSH-Red) (+22%). Superoxide dismutase activity was increased in muscle (+22%), while GSH-Px activity was significantly higher in liver (+28%), heart (+40%) and kidney (+45%) in Ai-treated compared with untreated group. Liver and muscle GSSH-Red activity was, respectively, 1.6- and 1.5-fold higher in Ai-treated than untreated diabetic group. Catalase activity was significantly increased in heart (+36%) and brain (+32%) in Ai-treated than untreated group. Ai treatment decreased plasma nitric oxide (−33%), carbonyls (−44%) and carotenoids (−68%) concentrations. In conclusion, this study indicates that Ajuga iva aqueous extract improves the antioxidant status by reducing lipid peroxidation and enhancing the antioxidant enzymes activities in plasma, erythrocytes and tissues of diabetic rats." @default.
- W2043918596 created "2016-06-24" @default.
- W2043918596 creator A5004459644 @default.
- W2043918596 creator A5046607696 @default.
- W2043918596 creator A5051551663 @default.
- W2043918596 creator A5064836936 @default.
- W2043918596 creator A5071516783 @default.
- W2043918596 creator A5074286741 @default.
- W2043918596 creator A5085584224 @default.
- W2043918596 date "2009-06-01" @default.
- W2043918596 modified "2023-10-17" @default.
- W2043918596 title "Antioxidant effect of Ajuga iva aqueous extract in streptozotocin-induced diabetic rats" @default.
- W2043918596 cites W1567614586 @default.
- W2043918596 cites W1775749144 @default.
- W2043918596 cites W1821918060 @default.
- W2043918596 cites W1969369643 @default.
- W2043918596 cites W1974986719 @default.
- W2043918596 cites W1983963835 @default.
- W2043918596 cites W1987596364 @default.
- W2043918596 cites W1993100066 @default.
- W2043918596 cites W1996098940 @default.
- W2043918596 cites W2007535892 @default.
- W2043918596 cites W2008343816 @default.
- W2043918596 cites W2022017066 @default.
- W2043918596 cites W2029222456 @default.
- W2043918596 cites W2031797666 @default.
- W2043918596 cites W2039232342 @default.
- W2043918596 cites W2045161916 @default.
- W2043918596 cites W2045479681 @default.
- W2043918596 cites W2047474084 @default.
- W2043918596 cites W2050271315 @default.
- W2043918596 cites W2067626923 @default.
- W2043918596 cites W2089752157 @default.
- W2043918596 cites W2093977973 @default.
- W2043918596 cites W2099785192 @default.
- W2043918596 cites W2123014029 @default.
- W2043918596 cites W2123409005 @default.
- W2043918596 cites W2127381333 @default.
- W2043918596 cites W2128334027 @default.
- W2043918596 cites W2134651645 @default.
- W2043918596 cites W2143698028 @default.
- W2043918596 cites W2148071155 @default.
- W2043918596 cites W2158399925 @default.
- W2043918596 cites W2228423988 @default.
- W2043918596 cites W2328234734 @default.
- W2043918596 cites W255295199 @default.
- W2043918596 cites W4232037616 @default.
- W2043918596 doi "https://doi.org/10.1016/j.phymed.2008.12.004" @default.
- W2043918596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19196501" @default.
- W2043918596 hasPublicationYear "2009" @default.
- W2043918596 type Work @default.
- W2043918596 sameAs 2043918596 @default.
- W2043918596 citedByCount "44" @default.
- W2043918596 countsByYear W20439185962012 @default.
- W2043918596 countsByYear W20439185962013 @default.
- W2043918596 countsByYear W20439185962014 @default.
- W2043918596 countsByYear W20439185962015 @default.
- W2043918596 countsByYear W20439185962016 @default.
- W2043918596 countsByYear W20439185962017 @default.
- W2043918596 countsByYear W20439185962018 @default.
- W2043918596 countsByYear W20439185962019 @default.
- W2043918596 countsByYear W20439185962020 @default.
- W2043918596 countsByYear W20439185962021 @default.
- W2043918596 countsByYear W20439185962022 @default.
- W2043918596 countsByYear W20439185962023 @default.
- W2043918596 crossrefType "journal-article" @default.
- W2043918596 hasAuthorship W2043918596A5004459644 @default.
- W2043918596 hasAuthorship W2043918596A5046607696 @default.
- W2043918596 hasAuthorship W2043918596A5051551663 @default.
- W2043918596 hasAuthorship W2043918596A5064836936 @default.
- W2043918596 hasAuthorship W2043918596A5071516783 @default.
- W2043918596 hasAuthorship W2043918596A5074286741 @default.
- W2043918596 hasAuthorship W2043918596A5085584224 @default.
- W2043918596 hasConcept C126322002 @default.
- W2043918596 hasConcept C134018914 @default.
- W2043918596 hasConcept C165069038 @default.
- W2043918596 hasConcept C181199279 @default.
- W2043918596 hasConcept C185592680 @default.
- W2043918596 hasConcept C2775838275 @default.
- W2043918596 hasConcept C2776231299 @default.
- W2043918596 hasConcept C2777352226 @default.
- W2043918596 hasConcept C2778004101 @default.
- W2043918596 hasConcept C2778760513 @default.
- W2043918596 hasConcept C2779280383 @default.
- W2043918596 hasConcept C2780829032 @default.
- W2043918596 hasConcept C2993539680 @default.
- W2043918596 hasConcept C538909803 @default.
- W2043918596 hasConcept C55493867 @default.
- W2043918596 hasConcept C555293320 @default.
- W2043918596 hasConcept C71924100 @default.
- W2043918596 hasConceptScore W2043918596C126322002 @default.
- W2043918596 hasConceptScore W2043918596C134018914 @default.
- W2043918596 hasConceptScore W2043918596C165069038 @default.
- W2043918596 hasConceptScore W2043918596C181199279 @default.
- W2043918596 hasConceptScore W2043918596C185592680 @default.
- W2043918596 hasConceptScore W2043918596C2775838275 @default.
- W2043918596 hasConceptScore W2043918596C2776231299 @default.
- W2043918596 hasConceptScore W2043918596C2777352226 @default.