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• W2043921872 abstract "Visualisation of nano-scale biomolecules aids understanding and development in molecular biology and nanotechnology. Detailed structure of nucleosomes adsorbed to mica has been captured in the absence of chemical-anchoring techniques, demonstrating the usefulness of non-contact atomic force microscopy (NC-AFM) for ultra-high resolution biomolecular imaging. NC-AFM offers significant advantages in terms of resolution, speed and ease of sample preparation when compared to techniques such as cryo-electron microscopy and X-ray crystallography. In the absence of chemical modification, detailed structure of DNA deposited on a gold substrate was observed for the first time using NC-AFM, opening up possibilities for investigating the electrical properties of unmodified DNA." @default.
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• W2043921872 date "2005-02-22" @default.
• W2043921872 modified "2023-10-12" @default.
• W2043921872 title "Ultra-high resolution imaging of DNA and nucleosomes using non-contact atomic force microscopy" @default.
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• W2043921872 doi "https://doi.org/10.1016/j.febslet.2005.02.028" @default.
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