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- W2043938412 abstract "Background: Interferon-alpha (IFN-alpha) and retinoic acid have been found to be active agents in the treatment of squamous-cell carcinomas. Recent experimental and clinical studies indicate an improvement of treatment results, if this agents are combined with irradiation. Material and Method: We report about a 53-year-old patient presenting with an advanced non-small-cell lung cancer. Systemical treatment with IFN-alpha and 13-cis retinoic acid was performed concurrently with radiotherapy. The patient’s follow-up, response and toxicity of this therapeutic regimen were evaluated. Result and Conclusions: The combination of IFN-alpha/retinoic acid with irradiation seems to be effective in the management of advanced non-small-cell carcinomas of the lung. However, in rare cases combined treatment with IFN-alpha and radiotherapy may be associated with increased side effects, especially radiation pneumonitis." @default.
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- W2043938412 date "1996-01-01" @default.
- W2043938412 modified "2023-09-26" @default.
- W2043938412 title "13-Cis Retinoic Acid, Interferon-alpha and Concomittant Irradiation in a Patient with Non-Small-Cell Lung Cancer – Description of Toxicity and Response" @default.
- W2043938412 doi "https://doi.org/10.1159/000218865" @default.
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