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- W2043938684 abstract "Antibodies in sera from five patients with hairy cell leukemia immunoprecipitated various membrane-fraction molecules form P3HR-I-EBV superinfected Raji lymphoblasts. A 19,000 dalton protein, p19, identified with EA-R antigenic specificity by serologically defined Burkitt's lymphoma antisera was also prominently recognized with hairy cell leukemia sera. In addition, a 120.000 dalton molecule associated with VCA specificity and a 28,000 dalton molecule associated with EA-D specificity were identified. A 35,000 dalton molecule from the EBV superinfected Raji cells was precipitated with antisera from patients who demonstrated abundant synthesis of a 35,000 dalton protein by their leukemic cells (p35+, p15− subset of patients). This finding was consistent with the hypothesis that the leukemic cells of the p35+, p15− subset of patients with hairy cell leukemia are transformed or infected with EBV, resulting in synthesis of an EBV-related protein." @default.
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- W2043938684 date "1981-01-01" @default.
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- W2043938684 title "Sera of patients with hairy cell leukemia immunoprecipitate EBV-related antigens" @default.
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- W2043938684 doi "https://doi.org/10.1016/0145-2126(81)90068-0" @default.
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