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- W2043949658 abstract "In this study of autonomic response to peripheral nerve afferent fiber excitation it was found that: Stimulation of sural or saphenous A- and C-fibers together produced a reflex discharge followed by a silent period and a secondary late C-fiber reflex discharge in lumbar segment white rami and in the renal nerve. By use of stimuli subthreshold for C-fibers and use of anodal block of A-fibers it was possible to stimulate A- and C-fibers independently. It was found that the C-fiber stimulation was responsible for the secondary reflex and increased overall efferent fiber activity. A rise in blood pressure was thus induced. A-fiber stimulation produced an earlier response and subsequent silent period. Following A-fiber stimulation the silent periods so reduced overall sympathetic discharge that depressor reactions occurred. Deafferentation of baroreceptors abolished the normally occurring pulsatile surges in efferent discharge which tended to obscure the silent period following mixed fiber and A-fiber stimulation. The silent period and depressor reaction became more evident on A-fiber stimulation. Excitation of C-fibers was clearly seen to produce no silent period and only the C-fiber reflex of relative long latency. Because of the latencies of response and presence of a silent period the responses recorded in this work were considered to be mediated through the medulla and not segmental spinal reactions. It was concluded that the A-fibers activate both a central excitatory and inhibitory system but the C-fibers only the excitatory complex." @default.
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- W2043949658 date "1970-05-01" @default.
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- W2043949658 title "Contribution of unmyelinated afferent excitation to sympathetic reflexes" @default.
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- W2043949658 doi "https://doi.org/10.1016/0006-8993(70)90158-7" @default.
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