Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043955506> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2043955506 endingPage "219" @default.
- W2043955506 startingPage "213" @default.
- W2043955506 abstract "Choriocarcinoma cell lines characteristically synthesize and secrete the α- and β-subunits of human chorionic gonadotropin (hCG), as well as the intact heterodimer. Treatment of one such cell line, BeWo, with 8-bromo-adenosine 3′:5′-cyclic monophosphate (8-Br-cAMP) causes at least a 10-fold increase in the concentration of the mRNA encoding each subunit. Changes in mRNA concentrations are associated with similar changes in transcription rates of both the CGα and CGβ genes, although the kinetics of their transcriptional responses are different. Transcription of the α-subunit gene increases rapidly and becomes maximal within 1 hr after addition of 8-Br-cAMP. By contrast, transcription of the CGβ gene increases slowly and progressively for at least 8 hr after treatment with 8-Br-cAMP. The slow transcriptional response of the CGβ gene(s) appears to be unique compared to that of other cAMP-responsive genes, and suggests that the cyclic nucleotide may regulate transcription of the CG genes by different mechanisms." @default.
- W2043955506 created "2016-06-24" @default.
- W2043955506 creator A5061032859 @default.
- W2043955506 creator A5066809107 @default.
- W2043955506 creator A5072154928 @default.
- W2043955506 date "1987-06-01" @default.
- W2043955506 modified "2023-09-23" @default.
- W2043955506 title "Cyclic AMP Regulates Transcription of the Genes Encoding Human Chorionic Gonadotropin with Different Kinetics" @default.
- W2043955506 cites W1495032438 @default.
- W2043955506 cites W1537080078 @default.
- W2043955506 cites W1575011694 @default.
- W2043955506 cites W1598530978 @default.
- W2043955506 cites W1601557881 @default.
- W2043955506 cites W1627508921 @default.
- W2043955506 cites W1674418446 @default.
- W2043955506 cites W1882849462 @default.
- W2043955506 cites W1906197854 @default.
- W2043955506 cites W1967946050 @default.
- W2043955506 cites W1981071038 @default.
- W2043955506 cites W1982905517 @default.
- W2043955506 cites W1984080990 @default.
- W2043955506 cites W1987208123 @default.
- W2043955506 cites W2031192188 @default.
- W2043955506 cites W2037737845 @default.
- W2043955506 cites W2042976701 @default.
- W2043955506 cites W2044794795 @default.
- W2043955506 cites W2048180296 @default.
- W2043955506 cites W2064419581 @default.
- W2043955506 cites W2079809058 @default.
- W2043955506 cites W2092245630 @default.
- W2043955506 cites W2096739053 @default.
- W2043955506 cites W2098671784 @default.
- W2043955506 cites W2158243093 @default.
- W2043955506 doi "https://doi.org/10.1089/dna.1987.6.213" @default.
- W2043955506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3036453" @default.
- W2043955506 hasPublicationYear "1987" @default.
- W2043955506 type Work @default.
- W2043955506 sameAs 2043955506 @default.
- W2043955506 citedByCount "66" @default.
- W2043955506 countsByYear W20439555062015 @default.
- W2043955506 countsByYear W20439555062016 @default.
- W2043955506 crossrefType "journal-article" @default.
- W2043955506 hasAuthorship W2043955506A5061032859 @default.
- W2043955506 hasAuthorship W2043955506A5066809107 @default.
- W2043955506 hasAuthorship W2043955506A5072154928 @default.
- W2043955506 hasConcept C104292427 @default.
- W2043955506 hasConcept C104317684 @default.
- W2043955506 hasConcept C105580179 @default.
- W2043955506 hasConcept C134018914 @default.
- W2043955506 hasConcept C138885662 @default.
- W2043955506 hasConcept C150194340 @default.
- W2043955506 hasConcept C153911025 @default.
- W2043955506 hasConcept C179926584 @default.
- W2043955506 hasConcept C2775948956 @default.
- W2043955506 hasConcept C2776991684 @default.
- W2043955506 hasConcept C41895202 @default.
- W2043955506 hasConcept C54355233 @default.
- W2043955506 hasConcept C71315377 @default.
- W2043955506 hasConcept C86803240 @default.
- W2043955506 hasConcept C95444343 @default.
- W2043955506 hasConceptScore W2043955506C104292427 @default.
- W2043955506 hasConceptScore W2043955506C104317684 @default.
- W2043955506 hasConceptScore W2043955506C105580179 @default.
- W2043955506 hasConceptScore W2043955506C134018914 @default.
- W2043955506 hasConceptScore W2043955506C138885662 @default.
- W2043955506 hasConceptScore W2043955506C150194340 @default.
- W2043955506 hasConceptScore W2043955506C153911025 @default.
- W2043955506 hasConceptScore W2043955506C179926584 @default.
- W2043955506 hasConceptScore W2043955506C2775948956 @default.
- W2043955506 hasConceptScore W2043955506C2776991684 @default.
- W2043955506 hasConceptScore W2043955506C41895202 @default.
- W2043955506 hasConceptScore W2043955506C54355233 @default.
- W2043955506 hasConceptScore W2043955506C71315377 @default.
- W2043955506 hasConceptScore W2043955506C86803240 @default.
- W2043955506 hasConceptScore W2043955506C95444343 @default.
- W2043955506 hasIssue "3" @default.
- W2043955506 hasLocation W20439555061 @default.
- W2043955506 hasLocation W20439555062 @default.
- W2043955506 hasOpenAccess W2043955506 @default.
- W2043955506 hasPrimaryLocation W20439555061 @default.
- W2043955506 hasRelatedWork W1972541767 @default.
- W2043955506 hasRelatedWork W1982262232 @default.
- W2043955506 hasRelatedWork W1985767170 @default.
- W2043955506 hasRelatedWork W2005531722 @default.
- W2043955506 hasRelatedWork W2009966535 @default.
- W2043955506 hasRelatedWork W2056172754 @default.
- W2043955506 hasRelatedWork W2172226517 @default.
- W2043955506 hasRelatedWork W2340167468 @default.
- W2043955506 hasRelatedWork W2420670753 @default.
- W2043955506 hasRelatedWork W2083042705 @default.
- W2043955506 hasVolume "6" @default.
- W2043955506 isParatext "false" @default.
- W2043955506 isRetracted "false" @default.
- W2043955506 magId "2043955506" @default.
- W2043955506 workType "article" @default.