Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043964736> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2043964736 endingPage "321" @default.
- W2043964736 startingPage "317" @default.
- W2043964736 abstract "Cyclooxygenase (COX) inhibitors were regarded as anticarcinogenic agents for lung cancer at least partly via PGE2; but these were based on cytokin stimulation experiment on A549 cell. In order to clarify whether COX inhibitors directly inhibit A549 cell, three COX inhibitors, NS398 (selective COX-2 inhibitor), SC560 (selective COX-1 inhibitor), and acetyl salicylic acid (ASA, non-selective COX inhibitor), were studied. NS398, and ASA, can inhibit PGE2 generation via COX-2 inhibition. The viability of A549 cell was assayed by MTT. However, without cytokin stimulation, all the three inhibitors (NS398 0.2-20 microM; SC560 1.0-100 nM; ASA 0.01-1.0 mM) were not able to inhibit A549 cell proliferation, in the other way round, NS398 promoted cell growth. And arachidonic acid (AA) and lipopolysaccharide (LPS) did not disturb the property of its growth. These data suggested that without cytokin stimulation, COX and PGE2 may not be the kernel molecules involved in A549 cell proliferation, and COX inhibitors could not inhibit A549 cell growth directly." @default.
- W2043964736 created "2016-06-24" @default.
- W2043964736 creator A5003128598 @default.
- W2043964736 creator A5041530586 @default.
- W2043964736 date "2006-05-01" @default.
- W2043964736 modified "2023-09-26" @default.
- W2043964736 title "Cyclooxygenase inhibitors not inhibit resting lung cancer A549 cell proliferation" @default.
- W2043964736 cites W1514451895 @default.
- W2043964736 cites W1972505498 @default.
- W2043964736 cites W1975809383 @default.
- W2043964736 cites W1985265301 @default.
- W2043964736 cites W2007209145 @default.
- W2043964736 cites W2011817759 @default.
- W2043964736 cites W2019632917 @default.
- W2043964736 cites W2028437871 @default.
- W2043964736 cites W2035952457 @default.
- W2043964736 cites W2050112422 @default.
- W2043964736 cites W2053388585 @default.
- W2043964736 cites W2055582785 @default.
- W2043964736 cites W2058194643 @default.
- W2043964736 cites W2072734944 @default.
- W2043964736 cites W2074072918 @default.
- W2043964736 cites W2076973370 @default.
- W2043964736 cites W2081642488 @default.
- W2043964736 cites W2093555416 @default.
- W2043964736 cites W2108516454 @default.
- W2043964736 cites W2126181424 @default.
- W2043964736 cites W2143930183 @default.
- W2043964736 cites W2163155801 @default.
- W2043964736 cites W2165523086 @default.
- W2043964736 cites W2185327065 @default.
- W2043964736 doi "https://doi.org/10.1016/j.plefa.2006.02.006" @default.
- W2043964736 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16618538" @default.
- W2043964736 hasPublicationYear "2006" @default.
- W2043964736 type Work @default.
- W2043964736 sameAs 2043964736 @default.
- W2043964736 citedByCount "28" @default.
- W2043964736 countsByYear W20439647362012 @default.
- W2043964736 countsByYear W20439647362013 @default.
- W2043964736 countsByYear W20439647362014 @default.
- W2043964736 countsByYear W20439647362015 @default.
- W2043964736 countsByYear W20439647362016 @default.
- W2043964736 countsByYear W20439647362017 @default.
- W2043964736 countsByYear W20439647362018 @default.
- W2043964736 countsByYear W20439647362022 @default.
- W2043964736 crossrefType "journal-article" @default.
- W2043964736 hasAuthorship W2043964736A5003128598 @default.
- W2043964736 hasAuthorship W2043964736A5041530586 @default.
- W2043964736 hasConcept C134018914 @default.
- W2043964736 hasConcept C1491633281 @default.
- W2043964736 hasConcept C181199279 @default.
- W2043964736 hasConcept C185592680 @default.
- W2043964736 hasConcept C24998067 @default.
- W2043964736 hasConcept C2777956040 @default.
- W2043964736 hasConcept C2778078955 @default.
- W2043964736 hasConcept C2779689624 @default.
- W2043964736 hasConcept C53227056 @default.
- W2043964736 hasConcept C55493867 @default.
- W2043964736 hasConcept C62112901 @default.
- W2043964736 hasConcept C81729549 @default.
- W2043964736 hasConcept C86803240 @default.
- W2043964736 hasConcept C98274493 @default.
- W2043964736 hasConceptScore W2043964736C134018914 @default.
- W2043964736 hasConceptScore W2043964736C1491633281 @default.
- W2043964736 hasConceptScore W2043964736C181199279 @default.
- W2043964736 hasConceptScore W2043964736C185592680 @default.
- W2043964736 hasConceptScore W2043964736C24998067 @default.
- W2043964736 hasConceptScore W2043964736C2777956040 @default.
- W2043964736 hasConceptScore W2043964736C2778078955 @default.
- W2043964736 hasConceptScore W2043964736C2779689624 @default.
- W2043964736 hasConceptScore W2043964736C53227056 @default.
- W2043964736 hasConceptScore W2043964736C55493867 @default.
- W2043964736 hasConceptScore W2043964736C62112901 @default.
- W2043964736 hasConceptScore W2043964736C81729549 @default.
- W2043964736 hasConceptScore W2043964736C86803240 @default.
- W2043964736 hasConceptScore W2043964736C98274493 @default.
- W2043964736 hasIssue "5" @default.
- W2043964736 hasLocation W20439647361 @default.
- W2043964736 hasLocation W20439647362 @default.
- W2043964736 hasOpenAccess W2043964736 @default.
- W2043964736 hasPrimaryLocation W20439647361 @default.
- W2043964736 hasRelatedWork W111468072 @default.
- W2043964736 hasRelatedWork W1504870841 @default.
- W2043964736 hasRelatedWork W1972134317 @default.
- W2043964736 hasRelatedWork W2003566827 @default.
- W2043964736 hasRelatedWork W2029916294 @default.
- W2043964736 hasRelatedWork W2032451328 @default.
- W2043964736 hasRelatedWork W2052709505 @default.
- W2043964736 hasRelatedWork W2064509099 @default.
- W2043964736 hasRelatedWork W2069591832 @default.
- W2043964736 hasRelatedWork W2353693964 @default.
- W2043964736 hasVolume "74" @default.
- W2043964736 isParatext "false" @default.
- W2043964736 isRetracted "false" @default.
- W2043964736 magId "2043964736" @default.
- W2043964736 workType "article" @default.