FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2043968560> ?p ?o ?g. }

• W2043968560 endingPage "471" @default.
• W2043968560 startingPage "464" @default.
• W2043968560 abstract "Problem To investigate whether thymic stromal lymphopoietin (TSLP) regulates the apoptosis of decidual γδ T cells and to elucidate the mechanism. Method of study Primary human decidual γδ T cells were treated with TSLP only or TSLP combined with different signaling inhibitors (STAT3, STAT5, AKT, and ERK). The levels of signal transduction and activation of transcription 3 (STAT3) tyrosine phosphorylation and caspase3 expression were determined using Western blot analysis, and the apoptosis of decidual γδ T cells was analyzed by flow cytometry. Results The proportions of γδ T cells in the peripheral circulation and in decidual CD3+ cell population in women with normal pregnancy were higher than the proportions of γδ T cells in either non-pregnant control or miscarriage. Decidual γδ T cells co-expressed the TSLP receptors (TSLPR) and IL-7Rα, and the expression of TSLPR in decidual γδ T cells was higher than that in decidual CD8+ and CD4+ T cells. Treatment with TSLP significantly suppressed the apoptosis of decidual γδ T cells and enhanced STAT3 phosphorylation. Moreover, STAT3, and not other inhibitors, completely abrogated the anti-apoptotic effect and expression of caspase3 in decidual γδ T cells induced by recombinant human TSLP. Conclusion These results suggest that TSLP may down-regulate caspase3 expression through activation of the STAT3 pathway, thereby suppressing the apoptosis of decidual γδ T cells." @default.
• W2043968560 created "2016-06-24" @default.
• W2043968560 creator A5006230341 @default.
• W2043968560 creator A5018863416 @default.
• W2043968560 creator A5031433768 @default.
• W2043968560 creator A5039840426 @default.
• W2043968560 creator A5052660758 @default.
• W2043968560 creator A5063372244 @default.
• W2043968560 creator A5087491415 @default.
• W2043968560 date "2013-09-13" @default.
• W2043968560 modified "2023-10-16" @default.
• W2043968560 title "Thymic Stromal Lymphopoietin Suppresses the Apoptosis of Decidual Gamma-delta T Cells via Regulation of the Signal Transduction and Activation of Transcription 3/Caspase-3 Signaling Pathway" @default.
• W2043968560 cites W1482475506 @default.
• W2043968560 cites W1503358451 @default.
• W2043968560 cites W1558665965 @default.
• W2043968560 cites W1570212613 @default.
• W2043968560 cites W1979026253 @default.
• W2043968560 cites W1980312883 @default.
• W2043968560 cites W1983895762 @default.
• W2043968560 cites W1987814011 @default.
• W2043968560 cites W1994846101 @default.
• W2043968560 cites W1995383519 @default.
• W2043968560 cites W2033006387 @default.
• W2043968560 cites W2035487673 @default.
• W2043968560 cites W2041001602 @default.
• W2043968560 cites W2053516651 @default.
• W2043968560 cites W2056657049 @default.
• W2043968560 cites W2059122942 @default.
• W2043968560 cites W2062424008 @default.
• W2043968560 cites W2062713327 @default.
• W2043968560 cites W2073851843 @default.
• W2043968560 cites W2088627901 @default.
• W2043968560 cites W2088813703 @default.
• W2043968560 cites W2099145786 @default.
• W2043968560 cites W2107553959 @default.
• W2043968560 cites W2113610605 @default.
• W2043968560 cites W2117746504 @default.
• W2043968560 cites W2122128999 @default.
• W2043968560 cites W2124684134 @default.
• W2043968560 cites W2124857960 @default.
• W2043968560 cites W2125021613 @default.
• W2043968560 cites W2137465231 @default.
• W2043968560 cites W2166748147 @default.
• W2043968560 cites W4245993254 @default.
• W2043968560 doi "https://doi.org/10.1111/aji.12158" @default.
• W2043968560 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24028796" @default.
• W2043968560 hasPublicationYear "2013" @default.
• W2043968560 type Work @default.
• W2043968560 sameAs 2043968560 @default.
• W2043968560 citedByCount "11" @default.
• W2043968560 countsByYear W20439685602016 @default.
• W2043968560 countsByYear W20439685602017 @default.
• W2043968560 countsByYear W20439685602019 @default.
• W2043968560 countsByYear W20439685602021 @default.
• W2043968560 countsByYear W20439685602023 @default.
• W2043968560 crossrefType "journal-article" @default.
• W2043968560 hasAuthorship W2043968560A5006230341 @default.
• W2043968560 hasAuthorship W2043968560A5018863416 @default.
• W2043968560 hasAuthorship W2043968560A5031433768 @default.
• W2043968560 hasAuthorship W2043968560A5039840426 @default.
• W2043968560 hasAuthorship W2043968560A5052660758 @default.
• W2043968560 hasAuthorship W2043968560A5063372244 @default.
• W2043968560 hasAuthorship W2043968560A5087491415 @default.
• W2043968560 hasConcept C16930146 @default.
• W2043968560 hasConcept C172680121 @default.
• W2043968560 hasConcept C185592680 @default.
• W2043968560 hasConcept C190283241 @default.
• W2043968560 hasConcept C203014093 @default.
• W2043968560 hasConcept C2776953305 @default.
• W2043968560 hasConcept C2777553839 @default.
• W2043968560 hasConcept C2778070265 @default.
• W2043968560 hasConcept C2778690821 @default.
• W2043968560 hasConcept C2778923194 @default.
• W2043968560 hasConcept C2779234561 @default.
• W2043968560 hasConcept C2780197806 @default.
• W2043968560 hasConcept C2781107390 @default.
• W2043968560 hasConcept C502942594 @default.
• W2043968560 hasConcept C54355233 @default.
• W2043968560 hasConcept C55493867 @default.
• W2043968560 hasConcept C62478195 @default.
• W2043968560 hasConcept C86803240 @default.
• W2043968560 hasConcept C95444343 @default.
• W2043968560 hasConceptScore W2043968560C16930146 @default.
• W2043968560 hasConceptScore W2043968560C172680121 @default.
• W2043968560 hasConceptScore W2043968560C185592680 @default.
• W2043968560 hasConceptScore W2043968560C190283241 @default.
• W2043968560 hasConceptScore W2043968560C203014093 @default.
• W2043968560 hasConceptScore W2043968560C2776953305 @default.
• W2043968560 hasConceptScore W2043968560C2777553839 @default.
• W2043968560 hasConceptScore W2043968560C2778070265 @default.
• W2043968560 hasConceptScore W2043968560C2778690821 @default.
• W2043968560 hasConceptScore W2043968560C2778923194 @default.
• W2043968560 hasConceptScore W2043968560C2779234561 @default.
• W2043968560 hasConceptScore W2043968560C2780197806 @default.
• W2043968560 hasConceptScore W2043968560C2781107390 @default.
• W2043968560 hasConceptScore W2043968560C502942594 @default.
• W2043968560 hasConceptScore W2043968560C54355233 @default.
• W2043968560 hasConceptScore W2043968560C55493867 @default.

• next