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- W2043971857 abstract "Networks of selectively neutral genotypes underlie the evolution of populations of replicators in constant environments. Previous theoretical analysis predicted that such populations will evolve toward highly connected regions of the genome space. We first study the evolution of populations of replicators on simple networks and quantify how the transient time to equilibrium depends on the initial distribution of sequences on the neutral network, on the topological properties of the latter, and on the mutation rate. Second, network neutrality is broken through the introduction of an energy for each sequence. This allows to study the competition between two features (neutrality and energetic stability) relevant for survival and subjected to different selective pressures. In cases where the two features are negatively correlated, the population experiences sudden migrations in the genome space for values of the relevant parameters that we calculate. The numerical study of larger networks indicates that the qualitative behavior to be expected in more realistic cases is already seen in representative examples of small networks." @default.
- W2043971857 created "2016-06-24" @default.
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- W2043971857 date "2009-12-14" @default.
- W2043971857 modified "2023-10-16" @default.
- W2043971857 title "Evolutionary dynamics on networks of selectively neutral genotypes: Effects of topology and sequence stability" @default.
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- W2043971857 doi "https://doi.org/10.1103/physreve.80.066112" @default.
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