FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044005149> ?p ?o ?g. }

• W2044005149 endingPage "e77303" @default.
• W2044005149 startingPage "e77303" @default.
• W2044005149 abstract "The emergence of high-throughput protein quantification methodologies has enabled the comprehensive characterization by longitudinal and cross-sectional studies of biological fluids under physiological and pathological conditions. In particular, the simultaneous investigation of cytokines and growth factors signaling pathways and their associated downstream effectors by integrated multiplexed approaches offers a powerful strategy to gain insights into biological networks and processes in living systems. A growing body of research indicates that bioactive molecules of human reproductive fluids, including human follicular fluid (hFF), may affect oocyte quality, fertilization and embryo development, thus potentially influencing the physiopathology of pregnancy-related conditions. In this work, an iTRAQ labeling strategy has been complemented with a multiplexed protein array approach to analyze hFFs with the aim to investigate biological processes and pathways related to in vitro fertilization (IVF) outcome. The iTRAQ labeling strategy lead to the quantification of 89 proteins, 30 of which were differentially expressed in hFFs with successful compared to unsuccessful IVF outcome. The targeted study, based on multiplexed antibody protein arrays, allowed the simultaneous quantification of 27 low abundance proteins, including growth factors, chemokines and cytokines endowed with pro- and anti-inflammatory activity. A significant number of differentially regulated proteins were involved in biological functions related to blood coagulation, acute phase response signaling and complement system. Overall, the present results provide an integrated overview of protein changes in hFFs associated to IVF outcome, thus improving current knowledge in reproductive medicine and fertility research." @default.
• W2044005149 created "2016-06-24" @default.
• W2044005149 creator A5017508831 @default.
• W2044005149 creator A5024209649 @default.
• W2044005149 creator A5024725865 @default.
• W2044005149 creator A5038053366 @default.
• W2044005149 creator A5051513902 @default.
• W2044005149 creator A5065462480 @default.
• W2044005149 creator A5071424520 @default.
• W2044005149 creator A5077280652 @default.
• W2044005149 creator A5080480480 @default.
• W2044005149 creator A5084553501 @default.
• W2044005149 date "2013-10-16" @default.
• W2044005149 modified "2023-09-27" @default.
• W2044005149 title "An Integrated Approach Based on Multiplexed Protein Array and iTRAQ Labeling for In-Depth Identification of Pathways Associated to IVF Outcome" @default.
• W2044005149 cites W1967090815 @default.
• W2044005149 cites W1974993338 @default.
• W2044005149 cites W1988640540 @default.
• W2044005149 cites W1997839295 @default.
• W2044005149 cites W2007309401 @default.
• W2044005149 cites W2013638514 @default.
• W2044005149 cites W2013876693 @default.
• W2044005149 cites W2015821770 @default.
• W2044005149 cites W2017991885 @default.
• W2044005149 cites W2021527386 @default.
• W2044005149 cites W2023190338 @default.
• W2044005149 cites W2027596874 @default.
• W2044005149 cites W2028526557 @default.
• W2044005149 cites W2037550429 @default.
• W2044005149 cites W2041317180 @default.
• W2044005149 cites W2052987321 @default.
• W2044005149 cites W2055474534 @default.
• W2044005149 cites W2061598286 @default.
• W2044005149 cites W2063344286 @default.
• W2044005149 cites W2071209122 @default.
• W2044005149 cites W2077506189 @default.
• W2044005149 cites W2086190847 @default.
• W2044005149 cites W2087747588 @default.
• W2044005149 cites W2095125400 @default.
• W2044005149 cites W2096167208 @default.
• W2044005149 cites W2097802875 @default.
• W2044005149 cites W2101397684 @default.
• W2044005149 cites W2101470801 @default.
• W2044005149 cites W2117206996 @default.
• W2044005149 cites W2124551895 @default.
• W2044005149 cites W2124905372 @default.
• W2044005149 cites W2131450997 @default.
• W2044005149 cites W2133465414 @default.
• W2044005149 cites W2136648677 @default.
• W2044005149 cites W2143696900 @default.
• W2044005149 cites W2145203144 @default.
• W2044005149 cites W2147027178 @default.
• W2044005149 cites W2148419961 @default.
• W2044005149 cites W2155647627 @default.
• W2044005149 cites W2158217645 @default.
• W2044005149 cites W2158784842 @default.
• W2044005149 cites W2167902484 @default.
• W2044005149 cites W2169897166 @default.
• W2044005149 cites W2309735559 @default.
• W2044005149 cites W56074922 @default.
• W2044005149 doi "https://doi.org/10.1371/journal.pone.0077303" @default.
• W2044005149 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3797768" @default.
• W2044005149 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24146976" @default.
• W2044005149 hasPublicationYear "2013" @default.
• W2044005149 type Work @default.
• W2044005149 sameAs 2044005149 @default.
• W2044005149 citedByCount "19" @default.
• W2044005149 countsByYear W20440051492014 @default.
• W2044005149 countsByYear W20440051492015 @default.
• W2044005149 countsByYear W20440051492016 @default.
• W2044005149 countsByYear W20440051492017 @default.
• W2044005149 countsByYear W20440051492018 @default.
• W2044005149 countsByYear W20440051492019 @default.
• W2044005149 countsByYear W20440051492020 @default.
• W2044005149 countsByYear W20440051492022 @default.
• W2044005149 countsByYear W20440051492023 @default.
• W2044005149 crossrefType "journal-article" @default.
• W2044005149 hasAuthorship W2044005149A5017508831 @default.
• W2044005149 hasAuthorship W2044005149A5024209649 @default.
• W2044005149 hasAuthorship W2044005149A5024725865 @default.
• W2044005149 hasAuthorship W2044005149A5038053366 @default.
• W2044005149 hasAuthorship W2044005149A5051513902 @default.
• W2044005149 hasAuthorship W2044005149A5065462480 @default.
• W2044005149 hasAuthorship W2044005149A5071424520 @default.
• W2044005149 hasAuthorship W2044005149A5077280652 @default.
• W2044005149 hasAuthorship W2044005149A5080480480 @default.
• W2044005149 hasAuthorship W2044005149A5084553501 @default.
• W2044005149 hasBestOaLocation W20440051491 @default.
• W2044005149 hasConcept C104317684 @default.
• W2044005149 hasConcept C150194340 @default.
• W2044005149 hasConcept C46111723 @default.
• W2044005149 hasConcept C55493867 @default.
• W2044005149 hasConcept C60644358 @default.
• W2044005149 hasConcept C70721500 @default.
• W2044005149 hasConcept C80311884 @default.
• W2044005149 hasConcept C86803240 @default.
• W2044005149 hasConcept C95444343 @default.
• W2044005149 hasConcept C9927688 @default.

• next