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• W2044005753 abstract "cDNA clones for chicken mitochondrial creatine kinase (Mi-CK) were isolated from a λgtll leg muscle cDNA library and sequenced. The deduced amino acid sequence showed 6 blocks of extensive homologies with the cytosolic creatine kinases and contained twenty N-terminal amino acids, with characteristic features of part of a mitochondrial presequence. The mature enzyme contained 380 amino acids with a calculated M of 43'195. RNA hybridization analysis showed corresponding Mi-CK transcripts in cardiac and skeletal muscle, but not in brain RNA. Within the 30 N-terminal amino acids purified brain Mi-CK contained 10 changes with respect to cardiac Mi-CK. Thus multiple isoproteins of mitochondrial creatine kinases of brain and striated muscle are encoded by multiple mRNA's." @default.
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• W2044005753 date "1988-02-01" @default.
• W2044005753 modified "2023-10-18" @default.
• W2044005753 title "Distinct tissue specific mitochondrial creatine kinases from chicken brain and striated muscle with a conserved CK framework" @default.
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• W2044005753 doi "https://doi.org/10.1016/0006-291x(88)90608-0" @default.
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