FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044012661> ?p ?o ?g. }

• W2044012661 endingPage "3304" @default.
• W2044012661 startingPage "3293" @default.
• W2044012661 abstract "The synthesis of a panel of seven nonsymmetric 5,10,15,20-tetraarylporphyrins, 13 symmetric and nonsymmetric 5,15-diarylporphyrins, and one 5,15-diarylchlorin is described. In vitro photodynamic activities on HCT116 human colon adenocarcinoma cells were evaluated by standard cytotoxicity assays. A predictive quantitative structure−activity relationship (QSAR) regression model, based on theoretical holistic molecular descriptors, of a series of 34 tetrapyrrolic photosensitizers (PSs), including the 24 compounds synthesized in this work, was developed to describe the relationship between structural features and photodynamic activity. The present study demonstrates that structural features significantly influence the photodynamic activity of tetrapyrrolic derivatives: diaryl compounds were more active with respect to the tetraarylporphyrins, and among the diaryl derivatives, hydroxy-substituted compounds were more effective than the corresponding methoxy-substituted ones. Furthermore, three monoarylporphyrins, isolated as byproducts during diarylporphyrin synthesis, were considered for both photodynamic and QSAR studies; surprisingly they were found to be particularly active photosensitizers." @default.
• W2044012661 created "2016-06-24" @default.
• W2044012661 creator A5032145374 @default.
• W2044012661 creator A5037756450 @default.
• W2044012661 creator A5040097564 @default.
• W2044012661 creator A5051300692 @default.
• W2044012661 creator A5053859930 @default.
• W2044012661 creator A5057686735 @default.
• W2044012661 creator A5072788998 @default.
• W2044012661 creator A5086535260 @default.
• W2044012661 date "2006-04-29" @default.
• W2044012661 modified "2023-09-24" @default.
• W2044012661 title "Comparison between 5,10,15,20-Tetraaryl- and 5,15-Diarylporphyrins as Photosensitizers: Synthesis, Photodynamic Activity, and Quantitative Structure−Activity Relationship Modeling" @default.
• W2044012661 cites W1545231783 @default.
• W2044012661 cites W1771776794 @default.
• W2044012661 cites W1964221211 @default.
• W2044012661 cites W1994681706 @default.
• W2044012661 cites W2015870870 @default.
• W2044012661 cites W2017191015 @default.
• W2044012661 cites W2022400681 @default.
• W2044012661 cites W2028002837 @default.
• W2044012661 cites W2030614491 @default.
• W2044012661 cites W2032570776 @default.
• W2044012661 cites W2041685462 @default.
• W2044012661 cites W2074681440 @default.
• W2044012661 cites W2077994443 @default.
• W2044012661 cites W2086190989 @default.
• W2044012661 cites W2087166462 @default.
• W2044012661 cites W2097989298 @default.
• W2044012661 cites W2111915031 @default.
• W2044012661 cites W2125235309 @default.
• W2044012661 cites W2134295461 @default.
• W2044012661 cites W2136443568 @default.
• W2044012661 cites W2140758554 @default.
• W2044012661 cites W2144735883 @default.
• W2044012661 cites W2148225055 @default.
• W2044012661 cites W2950113719 @default.
• W2044012661 doi "https://doi.org/10.1021/jm050997m" @default.
• W2044012661 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16722648" @default.
• W2044012661 hasPublicationYear "2006" @default.
• W2044012661 type Work @default.
• W2044012661 sameAs 2044012661 @default.
• W2044012661 citedByCount "59" @default.
• W2044012661 countsByYear W20440126612012 @default.
• W2044012661 countsByYear W20440126612013 @default.
• W2044012661 countsByYear W20440126612014 @default.
• W2044012661 countsByYear W20440126612016 @default.
• W2044012661 countsByYear W20440126612017 @default.
• W2044012661 countsByYear W20440126612018 @default.
• W2044012661 countsByYear W20440126612019 @default.
• W2044012661 countsByYear W20440126612020 @default.
• W2044012661 countsByYear W20440126612021 @default.
• W2044012661 countsByYear W20440126612022 @default.
• W2044012661 countsByYear W20440126612023 @default.
• W2044012661 crossrefType "journal-article" @default.
• W2044012661 hasAuthorship W2044012661A5032145374 @default.
• W2044012661 hasAuthorship W2044012661A5037756450 @default.
• W2044012661 hasAuthorship W2044012661A5040097564 @default.
• W2044012661 hasAuthorship W2044012661A5051300692 @default.
• W2044012661 hasAuthorship W2044012661A5053859930 @default.
• W2044012661 hasAuthorship W2044012661A5057686735 @default.
• W2044012661 hasAuthorship W2044012661A5072788998 @default.
• W2044012661 hasAuthorship W2044012661A5086535260 @default.
• W2044012661 hasBestOaLocation W20440126612 @default.
• W2044012661 hasConcept C109316439 @default.
• W2044012661 hasConcept C164126121 @default.
• W2044012661 hasConcept C164923092 @default.
• W2044012661 hasConcept C178790620 @default.
• W2044012661 hasConcept C178910836 @default.
• W2044012661 hasConcept C185592680 @default.
• W2044012661 hasConcept C193042331 @default.
• W2044012661 hasConcept C202751555 @default.
• W2044012661 hasConcept C21951064 @default.
• W2044012661 hasConcept C2779480358 @default.
• W2044012661 hasConcept C2781323092 @default.
• W2044012661 hasConcept C2781469039 @default.
• W2044012661 hasConcept C55493867 @default.
• W2044012661 hasConcept C71240020 @default.
• W2044012661 hasConceptScore W2044012661C109316439 @default.
• W2044012661 hasConceptScore W2044012661C164126121 @default.
• W2044012661 hasConceptScore W2044012661C164923092 @default.
• W2044012661 hasConceptScore W2044012661C178790620 @default.
• W2044012661 hasConceptScore W2044012661C178910836 @default.
• W2044012661 hasConceptScore W2044012661C185592680 @default.
• W2044012661 hasConceptScore W2044012661C193042331 @default.
• W2044012661 hasConceptScore W2044012661C202751555 @default.
• W2044012661 hasConceptScore W2044012661C21951064 @default.
• W2044012661 hasConceptScore W2044012661C2779480358 @default.
• W2044012661 hasConceptScore W2044012661C2781323092 @default.
• W2044012661 hasConceptScore W2044012661C2781469039 @default.
• W2044012661 hasConceptScore W2044012661C55493867 @default.
• W2044012661 hasConceptScore W2044012661C71240020 @default.
• W2044012661 hasIssue "11" @default.
• W2044012661 hasLocation W20440126611 @default.
• W2044012661 hasLocation W20440126612 @default.
• W2044012661 hasLocation W20440126613 @default.
• W2044012661 hasOpenAccess W2044012661 @default.
• W2044012661 hasPrimaryLocation W20440126611 @default.

• next