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- W2044015901 abstract "The formation of the dihydrobisfuran ring system uniquely representative of the aflatoxins among polyketide natural products is achieved in three net oxidative steps relating averufin (2) to versicolorin A (5). The first of these oxidative rearrangements carries the former to 1'-hydroxyversicolorone (3). Labeling experiments have placed several limitations on the mechanisms of reactions that can account for this transformation. Two viable possibilities involve radical or cationic intermediates whose fundamental reactivity toward rearrangement has been investigated in model reactions based on derivatives of 6,8-di-O-methylaverufin (20, X=H)." @default.
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- W2044015901 date "1989-01-01" @default.
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- W2044015901 title "Reaction Models of the Oxidative Rearrangement of Averufin to 1'- Hydroxyversicolorone: The First Step in Dihydrobisfuran Formation in Aflatoxin Biosynthesis" @default.
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- W2044015901 doi "https://doi.org/10.1016/s0040-4020(01)83431-1" @default.
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