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- W2044072912 abstract "A patient is described who had evidence of abnormal fibrinogen, but who had neither a bleeding tendency nor a history of thrombosis. Laboratory studies disclosed markedly prolonged clotting times with either thrombin, Reptilase or Arvin, and the addition of calcium or Protamine sulfate provided partial correction of the prolonged clotting times. Immunequantitation demonstrated normal amount of fibrinogen-related antigens in plasma. The same coagulation abnormalities were demonstrated in blood samples from the father, but not the mother. This inherited defect seems to affect fibrin formation mainly through an impaired polymerization." @default.
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- W2044072912 date "1973-03-01" @default.
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- W2044072912 title "Fibrinogen Iowa City : An abnormal fibrinogen with no clinical symptoms" @default.
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- W2044072912 doi "https://doi.org/10.1016/0049-3848(73)90089-3" @default.
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