Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044073033> ?p ?o ?g. }
- W2044073033 endingPage "362" @default.
- W2044073033 startingPage "350" @default.
- W2044073033 abstract "Abstract The present study evaluates the in vitro biomedical performance of an electrospun, flexible, and cotton wool‐like poly(lactide‐ co ‐glycolide) (PLGA)/amorphous tricalcium phosphate (ATCP) nanocomposite. Experiments on in vitro biomineralization, applicability in model defects and a cell culture study with human mesenchymal stem cells (hMSC) allowed assessing the application of the material for potential use as a bone graft. Scaffolds with different flame made ATCP nanoparticle loadings were prepared by electrospinning of a PLGA‐based composite. Immersion in simulated body fluid showed significant deposition of a hydroxyapatite layer only on the surface of ATCP doped PLGA (up to 175% mass gain within 15 days for PLGA/ATCP 60:40). Proliferation and osteogenic differentiation of hMSC on different nanocomposites were assessed by incubating cells in osteogenic medium for 4 weeks. Proper adhesion and an unaffected morphology of the cells were observed by confocal laser scanning microscopy for all samples. Fluorometric quantification of dsDNA and analysis of ALP activity revealed no significant difference between the tested scaffolds and excluded any acute cytotoxic effects of the nanoparticles. The osteocalcin content for all scaffolds was 0.12–0.19 ng/ng DNA confirming osteogenic differentiation of human mesenchymal stem cells on these flexible bone implants. © 2007 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 2008" @default.
- W2044073033 created "2016-06-24" @default.
- W2044073033 creator A5007693485 @default.
- W2044073033 creator A5020744211 @default.
- W2044073033 creator A5032145937 @default.
- W2044073033 creator A5032584253 @default.
- W2044073033 creator A5033717261 @default.
- W2044073033 creator A5035272873 @default.
- W2044073033 creator A5052877317 @default.
- W2044073033 creator A5082085375 @default.
- W2044073033 date "2007-07-06" @default.
- W2044073033 modified "2023-10-17" @default.
- W2044073033 title "Cotton wool-like nanocomposite biomaterials prepared by electrospinning:<i>In vitro</i>bioactivity and osteogenic differentiation of human mesenchymal stem cells" @default.
- W2044073033 cites W124663190 @default.
- W2044073033 cites W1965676278 @default.
- W2044073033 cites W1966476051 @default.
- W2044073033 cites W1990764536 @default.
- W2044073033 cites W1991553070 @default.
- W2044073033 cites W1994281287 @default.
- W2044073033 cites W1998489061 @default.
- W2044073033 cites W2005642158 @default.
- W2044073033 cites W2006239006 @default.
- W2044073033 cites W2007566603 @default.
- W2044073033 cites W2009416595 @default.
- W2044073033 cites W2013286736 @default.
- W2044073033 cites W2013429967 @default.
- W2044073033 cites W2014241785 @default.
- W2044073033 cites W2014637539 @default.
- W2044073033 cites W2017224869 @default.
- W2044073033 cites W2023953000 @default.
- W2044073033 cites W2025188006 @default.
- W2044073033 cites W2030550786 @default.
- W2044073033 cites W2032260996 @default.
- W2044073033 cites W2036177694 @default.
- W2044073033 cites W2042755153 @default.
- W2044073033 cites W2046066333 @default.
- W2044073033 cites W2046232956 @default.
- W2044073033 cites W2047322445 @default.
- W2044073033 cites W2047833244 @default.
- W2044073033 cites W2048357511 @default.
- W2044073033 cites W2050141506 @default.
- W2044073033 cites W2053134886 @default.
- W2044073033 cites W2053490395 @default.
- W2044073033 cites W2072779462 @default.
- W2044073033 cites W2073480775 @default.
- W2044073033 cites W2082654903 @default.
- W2044073033 cites W2084992259 @default.
- W2044073033 cites W2085495836 @default.
- W2044073033 cites W2088697330 @default.
- W2044073033 cites W2097922419 @default.
- W2044073033 cites W2103745164 @default.
- W2044073033 cites W2113147520 @default.
- W2044073033 cites W2120262551 @default.
- W2044073033 cites W2122932077 @default.
- W2044073033 cites W2132309525 @default.
- W2044073033 cites W2133951784 @default.
- W2044073033 cites W2136652158 @default.
- W2044073033 cites W2141819286 @default.
- W2044073033 cites W2142229749 @default.
- W2044073033 cites W2152621785 @default.
- W2044073033 cites W2155511415 @default.
- W2044073033 cites W2157248428 @default.
- W2044073033 cites W2166985171 @default.
- W2044073033 cites W2199338994 @default.
- W2044073033 cites W2460460489 @default.
- W2044073033 cites W4242249115 @default.
- W2044073033 cites W4242740909 @default.
- W2044073033 doi "https://doi.org/10.1002/jbm.b.30878" @default.
- W2044073033 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17618506" @default.
- W2044073033 hasPublicationYear "2007" @default.
- W2044073033 type Work @default.
- W2044073033 sameAs 2044073033 @default.
- W2044073033 citedByCount "109" @default.
- W2044073033 countsByYear W20440730332012 @default.
- W2044073033 countsByYear W20440730332013 @default.
- W2044073033 countsByYear W20440730332014 @default.
- W2044073033 countsByYear W20440730332015 @default.
- W2044073033 countsByYear W20440730332016 @default.
- W2044073033 countsByYear W20440730332017 @default.
- W2044073033 countsByYear W20440730332018 @default.
- W2044073033 countsByYear W20440730332019 @default.
- W2044073033 countsByYear W20440730332020 @default.
- W2044073033 countsByYear W20440730332021 @default.
- W2044073033 countsByYear W20440730332022 @default.
- W2044073033 countsByYear W20440730332023 @default.
- W2044073033 crossrefType "journal-article" @default.
- W2044073033 hasAuthorship W2044073033A5007693485 @default.
- W2044073033 hasAuthorship W2044073033A5020744211 @default.
- W2044073033 hasAuthorship W2044073033A5032145937 @default.
- W2044073033 hasAuthorship W2044073033A5032584253 @default.
- W2044073033 hasAuthorship W2044073033A5033717261 @default.
- W2044073033 hasAuthorship W2044073033A5035272873 @default.
- W2044073033 hasAuthorship W2044073033A5052877317 @default.
- W2044073033 hasAuthorship W2044073033A5082085375 @default.
- W2044073033 hasConcept C114874019 @default.
- W2044073033 hasConcept C131075544 @default.
- W2044073033 hasConcept C136229726 @default.
- W2044073033 hasConcept C144796933 @default.