Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044094057> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2044094057 endingPage "3979" @default.
- W2044094057 startingPage "3975" @default.
- W2044094057 abstract "Mice were immunized intravenously with suboptimal numbers (3.5-5 X 10(5)) of sheep erythrocytes together with various anti-Ia antisera or with sheep erythrocytes alone, and the primary IgM and IgG plaque-forming cell responses were assayed 6 days later9 A/J (H-2a) mice given 5 X 10(5) sheep erythrocytes together with as little as 0.4 mul of a (129 X A.TH)F1 anti-A.TL (anti-Iak) antiserum developed 2-3 times as many IgM and IGG plaque-forming cells as mice injected with antigen alone or together with various antisera not containing anti-Ia antibodies. Similar results were obtained with BALB/c (H-2d) mice and a (C3H X LG/Ckc)F1 anti-C3H. OH (anti-Iad) antiserum plus sheep erythrocytes. In the case of the anti-Iad antiserum, the potentiating activity could be absorbed with C3H. OH (Id) but not C3H(Ik) spleen cells, demonstrating that the active antibodies were specific for the Id region. Antiserum to I-Jk subregion-coded determinants was tested in A/J (I-Jk) mice and found to also potentiate 2- to 3-fold the plaque-forming cell response to suboptimal erythrocyte immunization. This antiserum [(BIO.A(3R) X DBA/2)F1 anti-B10.(5R)] failed to potentiate responses in BALB/c (I-Jd) mice, as expected on a genetic basis. The potentiating antibodies could be removed by absorption with B10.BR (I-Jk) but not B10 (I-Jb) spleen cells, also confirming the I-J specificity of the activity. The interference of anti-I-J antibodies with T lymphocyte suppressor mechanisms is prposed as a possible explanation for this phenomenon." @default.
- W2044094057 created "2016-06-24" @default.
- W2044094057 creator A5001497872 @default.
- W2044094057 creator A5019713118 @default.
- W2044094057 creator A5061890650 @default.
- W2044094057 creator A5088777789 @default.
- W2044094057 date "1977-09-01" @default.
- W2044094057 modified "2023-09-25" @default.
- W2044094057 title "Potentiation of a primary in vivo antibody response by alloantisera against gene products of the I region of the H-2 complex." @default.
- W2044094057 cites W1597280377 @default.
- W2044094057 cites W1655303875 @default.
- W2044094057 cites W1818832990 @default.
- W2044094057 cites W1969264080 @default.
- W2044094057 cites W1973949275 @default.
- W2044094057 cites W1983256549 @default.
- W2044094057 cites W1998446920 @default.
- W2044094057 cites W1999258990 @default.
- W2044094057 cites W2052912052 @default.
- W2044094057 cites W2063454253 @default.
- W2044094057 cites W2076243094 @default.
- W2044094057 cites W2088902614 @default.
- W2044094057 cites W2105993705 @default.
- W2044094057 cites W2115238418 @default.
- W2044094057 cites W2133548204 @default.
- W2044094057 cites W2140250150 @default.
- W2044094057 cites W2142393704 @default.
- W2044094057 cites W2145727693 @default.
- W2044094057 cites W2150370198 @default.
- W2044094057 cites W2169874712 @default.
- W2044094057 cites W3027998753 @default.
- W2044094057 doi "https://doi.org/10.1073/pnas.74.9.3975" @default.
- W2044094057 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/431808" @default.
- W2044094057 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/410029" @default.
- W2044094057 hasPublicationYear "1977" @default.
- W2044094057 type Work @default.
- W2044094057 sameAs 2044094057 @default.
- W2044094057 citedByCount "33" @default.
- W2044094057 crossrefType "journal-article" @default.
- W2044094057 hasAuthorship W2044094057A5001497872 @default.
- W2044094057 hasAuthorship W2044094057A5019713118 @default.
- W2044094057 hasAuthorship W2044094057A5061890650 @default.
- W2044094057 hasAuthorship W2044094057A5088777789 @default.
- W2044094057 hasBestOaLocation W20440940572 @default.
- W2044094057 hasConcept C147483822 @default.
- W2044094057 hasConcept C153911025 @default.
- W2044094057 hasConcept C159654299 @default.
- W2044094057 hasConcept C203014093 @default.
- W2044094057 hasConcept C207001950 @default.
- W2044094057 hasConcept C2780801004 @default.
- W2044094057 hasConcept C2780931953 @default.
- W2044094057 hasConcept C54355233 @default.
- W2044094057 hasConcept C86803240 @default.
- W2044094057 hasConcept C91523082 @default.
- W2044094057 hasConceptScore W2044094057C147483822 @default.
- W2044094057 hasConceptScore W2044094057C153911025 @default.
- W2044094057 hasConceptScore W2044094057C159654299 @default.
- W2044094057 hasConceptScore W2044094057C203014093 @default.
- W2044094057 hasConceptScore W2044094057C207001950 @default.
- W2044094057 hasConceptScore W2044094057C2780801004 @default.
- W2044094057 hasConceptScore W2044094057C2780931953 @default.
- W2044094057 hasConceptScore W2044094057C54355233 @default.
- W2044094057 hasConceptScore W2044094057C86803240 @default.
- W2044094057 hasConceptScore W2044094057C91523082 @default.
- W2044094057 hasIssue "9" @default.
- W2044094057 hasLocation W20440940571 @default.
- W2044094057 hasLocation W20440940572 @default.
- W2044094057 hasLocation W20440940573 @default.
- W2044094057 hasLocation W20440940574 @default.
- W2044094057 hasOpenAccess W2044094057 @default.
- W2044094057 hasPrimaryLocation W20440940571 @default.
- W2044094057 hasRelatedWork W131348366 @default.
- W2044094057 hasRelatedWork W1589286368 @default.
- W2044094057 hasRelatedWork W1973692620 @default.
- W2044094057 hasRelatedWork W2005558852 @default.
- W2044094057 hasRelatedWork W2057438098 @default.
- W2044094057 hasRelatedWork W2073023727 @default.
- W2044094057 hasRelatedWork W2082213190 @default.
- W2044094057 hasRelatedWork W2087539308 @default.
- W2044094057 hasRelatedWork W2359730144 @default.
- W2044094057 hasRelatedWork W2402858051 @default.
- W2044094057 hasVolume "74" @default.
- W2044094057 isParatext "false" @default.
- W2044094057 isRetracted "false" @default.
- W2044094057 magId "2044094057" @default.
- W2044094057 workType "article" @default.