FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044135800> ?p ?o ?g. }

• W2044135800 endingPage "66" @default.
• W2044135800 startingPage "58" @default.
• W2044135800 abstract "Background: Eosinophilic bronchitis is a common cause of chronic cough, which like asthma is characterized by sputum eosinophilia, but unlike asthma there is no variable airflow obstruction or airway hyperresponsiveness. We tested the hypothesis that the different airway function in patients with eosinophilic bronchitis and asthma could be caused by an imbalance in the production of bronchoconstrictor (LTC 4 ) and bronchoprotective (prostaglandin E 2 ; PGE 2 ) lipid mediators. Methods: We measured cytokines levels, proinflammatory mediators and eicosanoids concentration in sputum from 13 subjects with nonasthmatic eosinophilic bronchitis, 13 subjects with asthma, and 11 healthy control subjects. Cytokines mRNA levels were measured by real time PCR, proinflammatory mediators, PGE 2 , and LTC 4 were measured by enzyme immunoassays. Results: The median sputum eosinophil count was not statistically different in patients with asthma (7.95%) and eosinophilic bronchitis (15.29%). The levels of mRNA specific to interleukin‐5 (IL‐5), IL‐4, IL‐10, IL‐13, interferon γ (IFN‐γ), IL‐2, vascular endothelial growth factor and transforming growth factor β were similar in both conditions. In addition, no differences were found between asthma and eosinophilic bronchitis in proinflammatory cytokines, such as IL‐8, IFN‐γ and tumor necrosis factor α (TNF‐α) levels. Sputum cysteinyl‐leukotrienes concentration was raised both in eosinophilic bronchitis and asthma patients. We found that induced sputum PGE 2 concentrations were significantly increased in subjects with eosinophilic bronchitis (838.3 ± 612 pg/ml) when compared with asthmatic (7.54 ± 2.14 pg/ml) and healthy subjects (4 ± 1.3 pg/ml). Conclusion: This data suggest that the difference in airway function observed in subjects with eosinophilic bronchitis and asthma could be due to differences in PGE 2 production in the airways." @default.
• W2044135800 created "2016-06-24" @default.
• W2044135800 creator A5021497445 @default.
• W2044135800 creator A5023676098 @default.
• W2044135800 creator A5025399535 @default.
• W2044135800 creator A5028832295 @default.
• W2044135800 creator A5072541684 @default.
• W2044135800 creator A5076224742 @default.
• W2044135800 creator A5080452404 @default.
• W2044135800 creator A5089377771 @default.
• W2044135800 date "2007-12-05" @default.
• W2044135800 modified "2023-10-14" @default.
• W2044135800 title "Increased prostaglandin E₂levels in the airway of patients with eosinophilic bronchitis" @default.
• W2044135800 cites W1847502419 @default.
• W2044135800 cites W1971569966 @default.
• W2044135800 cites W1973188423 @default.
• W2044135800 cites W1977346941 @default.
• W2044135800 cites W1978177122 @default.
• W2044135800 cites W1978730128 @default.
• W2044135800 cites W1986420435 @default.
• W2044135800 cites W1990174772 @default.
• W2044135800 cites W1997214991 @default.
• W2044135800 cites W1999499557 @default.
• W2044135800 cites W2003251689 @default.
• W2044135800 cites W2006347291 @default.
• W2044135800 cites W2016329784 @default.
• W2044135800 cites W2019856457 @default.
• W2044135800 cites W2027697280 @default.
• W2044135800 cites W2029514792 @default.
• W2044135800 cites W2030896704 @default.
• W2044135800 cites W2043137885 @default.
• W2044135800 cites W2045770017 @default.
• W2044135800 cites W2055599580 @default.
• W2044135800 cites W2056041894 @default.
• W2044135800 cites W2066578176 @default.
• W2044135800 cites W2074960987 @default.
• W2044135800 cites W2076787271 @default.
• W2044135800 cites W2097491679 @default.
• W2044135800 cites W2109781176 @default.
• W2044135800 cites W2121216118 @default.
• W2044135800 cites W2125252801 @default.
• W2044135800 cites W2131644278 @default.
• W2044135800 cites W2133162139 @default.
• W2044135800 cites W2134710417 @default.
• W2044135800 cites W2146066221 @default.
• W2044135800 cites W2146463187 @default.
• W2044135800 cites W2150336758 @default.
• W2044135800 cites W2163624955 @default.
• W2044135800 cites W2167950725 @default.
• W2044135800 cites W4236639597 @default.
• W2044135800 doi "https://doi.org/10.1111/j.1398-9995.2007.01515.x" @default.
• W2044135800 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17961198" @default.
• W2044135800 hasPublicationYear "2007" @default.
• W2044135800 type Work @default.
• W2044135800 sameAs 2044135800 @default.
• W2044135800 citedByCount "20" @default.
• W2044135800 countsByYear W20441358002012 @default.
• W2044135800 countsByYear W20441358002013 @default.
• W2044135800 countsByYear W20441358002015 @default.
• W2044135800 countsByYear W20441358002017 @default.
• W2044135800 countsByYear W20441358002018 @default.
• W2044135800 countsByYear W20441358002020 @default.
• W2044135800 countsByYear W20441358002021 @default.
• W2044135800 countsByYear W20441358002022 @default.
• W2044135800 crossrefType "journal-article" @default.
• W2044135800 hasAuthorship W2044135800A5021497445 @default.
• W2044135800 hasAuthorship W2044135800A5023676098 @default.
• W2044135800 hasAuthorship W2044135800A5025399535 @default.
• W2044135800 hasAuthorship W2044135800A5028832295 @default.
• W2044135800 hasAuthorship W2044135800A5072541684 @default.
• W2044135800 hasAuthorship W2044135800A5076224742 @default.
• W2044135800 hasAuthorship W2044135800A5080452404 @default.
• W2044135800 hasAuthorship W2044135800A5089377771 @default.
• W2044135800 hasConcept C126322002 @default.
• W2044135800 hasConcept C142724271 @default.
• W2044135800 hasConcept C164027704 @default.
• W2044135800 hasConcept C203014093 @default.
• W2044135800 hasConcept C2776042228 @default.
• W2044135800 hasConcept C2776178081 @default.
• W2044135800 hasConcept C2776301714 @default.
• W2044135800 hasConcept C2776914184 @default.
• W2044135800 hasConcept C2777037409 @default.
• W2044135800 hasConcept C2777129736 @default.
• W2044135800 hasConcept C2777714996 @default.
• W2044135800 hasConcept C2779758542 @default.
• W2044135800 hasConcept C2780942278 @default.
• W2044135800 hasConcept C2781069245 @default.
• W2044135800 hasConcept C2992694001 @default.
• W2044135800 hasConcept C71924100 @default.
• W2044135800 hasConceptScore W2044135800C126322002 @default.
• W2044135800 hasConceptScore W2044135800C142724271 @default.
• W2044135800 hasConceptScore W2044135800C164027704 @default.
• W2044135800 hasConceptScore W2044135800C203014093 @default.
• W2044135800 hasConceptScore W2044135800C2776042228 @default.
• W2044135800 hasConceptScore W2044135800C2776178081 @default.
• W2044135800 hasConceptScore W2044135800C2776301714 @default.
• W2044135800 hasConceptScore W2044135800C2776914184 @default.
• W2044135800 hasConceptScore W2044135800C2777037409 @default.

• next