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- W2044156290 abstract "Infantile myofibromatosis is the most common fibrous tumor of infancy. Solitary or generalized myofibromas without visceral involvement usually regress within a few months. The multifocal disease infantile generalized myofibromatosis, with visceral involvement, is associated with a significant mortality due to the effect of tumors on vital organs. We report a case of infantile generalized myofibromatosis with visceral involvement, including 2 right atrium tumors. The infant expressed high circulating vascular endothelial growth factor and fibroblast growth factor-2 levels, and interferon alpha-2b was started as antiangiogenic treatment, aimed at triggering regression of the life-threatening cardiac lesions. The tumors regressed and vascular endothelial growth factor and fibroblast growth factor-2 levels were reduced after treatment discontinuation." @default.
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- W2044156290 date "2008-02-01" @default.
- W2044156290 modified "2023-10-16" @default.
- W2044156290 title "Remission of Infantile Generalized Myofibromatosis After Interferon Alpha Therapy" @default.
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- W2044156290 doi "https://doi.org/10.1097/mph.0b013e31815e62bb" @default.
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