FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2044171486> ?p ?o ?g. }

• W2044171486 endingPage "124" @default.
• W2044171486 startingPage "115" @default.
• W2044171486 abstract "Ethambutol (EMB), widely used in the treatment of tuberculosis, has been reported to cause Leber’s hereditary optic neuropathy in patients carrying mitochondrial DNA mutations. We study the effect of EMB on mitochondrial metabolism in fibroblasts from controls and from a man carrying an OPA1 mutation, in whom the drug induced the development of autosomal dominant optic atrophy (ADOA). EMB produced a mitochondrial coupling defect together with a 25% reduction in complex IV activity. EMB induced the formation of vacuoles associated with decreased mitochondrial membrane potential and increased fragmentation of the mitochondrial network. Mitochondrial genetic variations may therefore be predisposing factors in EMB-induced ocular injury." @default.
• W2044171486 created "2016-06-24" @default.
• W2044171486 creator A5015665453 @default.
• W2044171486 creator A5018701159 @default.
• W2044171486 creator A5020075483 @default.
• W2044171486 creator A5026093056 @default.
• W2044171486 creator A5027313965 @default.
• W2044171486 creator A5046445493 @default.
• W2044171486 creator A5049879967 @default.
• W2044171486 creator A5056889555 @default.
• W2044171486 creator A5069738750 @default.
• W2044171486 creator A5074317606 @default.
• W2044171486 creator A5077338184 @default.
• W2044171486 creator A5086154942 @default.
• W2044171486 date "2010-03-01" @default.
• W2044171486 modified "2023-10-10" @default.
• W2044171486 title "Ethambutol-induced optic neuropathy linked to OPA1 mutation and mitochondrial toxicity" @default.
• W2044171486 cites W1525179799 @default.
• W2044171486 cites W1570420082 @default.
• W2044171486 cites W1585407713 @default.
• W2044171486 cites W1964682506 @default.
• W2044171486 cites W1966475640 @default.
• W2044171486 cites W1967402588 @default.
• W2044171486 cites W1967445833 @default.
• W2044171486 cites W1971166592 @default.
• W2044171486 cites W1984093722 @default.
• W2044171486 cites W1986720672 @default.
• W2044171486 cites W1986996580 @default.
• W2044171486 cites W1995576209 @default.
• W2044171486 cites W2005033621 @default.
• W2044171486 cites W2005247243 @default.
• W2044171486 cites W2011128355 @default.
• W2044171486 cites W2018473673 @default.
• W2044171486 cites W2026428819 @default.
• W2044171486 cites W2028376842 @default.
• W2044171486 cites W2032416810 @default.
• W2044171486 cites W2039795722 @default.
• W2044171486 cites W2052488557 @default.
• W2044171486 cites W2053558089 @default.
• W2044171486 cites W2053993266 @default.
• W2044171486 cites W2058837644 @default.
• W2044171486 cites W2062502672 @default.
• W2044171486 cites W2073788301 @default.
• W2044171486 cites W2078660035 @default.
• W2044171486 cites W2084448079 @default.
• W2044171486 cites W2086150823 @default.
• W2044171486 cites W2094113524 @default.
• W2044171486 cites W2094196660 @default.
• W2044171486 cites W2103640382 @default.
• W2044171486 cites W2109942343 @default.
• W2044171486 cites W2130758099 @default.
• W2044171486 cites W2140663895 @default.
• W2044171486 cites W2151457909 @default.
• W2044171486 cites W2152031063 @default.
• W2044171486 cites W2157250831 @default.
• W2044171486 cites W2168124117 @default.
• W2044171486 cites W4321060700 @default.
• W2044171486 cites W91761544 @default.
• W2044171486 doi "https://doi.org/10.1016/j.mito.2009.11.004" @default.
• W2044171486 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19900585" @default.
• W2044171486 hasPublicationYear "2010" @default.
• W2044171486 type Work @default.
• W2044171486 sameAs 2044171486 @default.
• W2044171486 citedByCount "42" @default.
• W2044171486 countsByYear W20441714862013 @default.
• W2044171486 countsByYear W20441714862014 @default.
• W2044171486 countsByYear W20441714862015 @default.
• W2044171486 countsByYear W20441714862016 @default.
• W2044171486 countsByYear W20441714862017 @default.
• W2044171486 countsByYear W20441714862018 @default.
• W2044171486 countsByYear W20441714862020 @default.
• W2044171486 countsByYear W20441714862021 @default.
• W2044171486 countsByYear W20441714862022 @default.
• W2044171486 countsByYear W20441714862023 @default.
• W2044171486 crossrefType "journal-article" @default.
• W2044171486 hasAuthorship W2044171486A5015665453 @default.
• W2044171486 hasAuthorship W2044171486A5018701159 @default.
• W2044171486 hasAuthorship W2044171486A5020075483 @default.
• W2044171486 hasAuthorship W2044171486A5026093056 @default.
• W2044171486 hasAuthorship W2044171486A5027313965 @default.
• W2044171486 hasAuthorship W2044171486A5046445493 @default.
• W2044171486 hasAuthorship W2044171486A5049879967 @default.
• W2044171486 hasAuthorship W2044171486A5056889555 @default.
• W2044171486 hasAuthorship W2044171486A5069738750 @default.
• W2044171486 hasAuthorship W2044171486A5074317606 @default.
• W2044171486 hasAuthorship W2044171486A5077338184 @default.
• W2044171486 hasAuthorship W2044171486A5086154942 @default.
• W2044171486 hasConcept C102568950 @default.
• W2044171486 hasConcept C104317684 @default.
• W2044171486 hasConcept C105702510 @default.
• W2044171486 hasConcept C190062978 @default.
• W2044171486 hasConcept C24586158 @default.
• W2044171486 hasConcept C2775843808 @default.
• W2044171486 hasConcept C2776228421 @default.
• W2044171486 hasConcept C2777071529 @default.
• W2044171486 hasConcept C2778233873 @default.
• W2044171486 hasConcept C2780837183 @default.
• W2044171486 hasConcept C2781172350 @default.

• next